布托啡诺联合地塞米松预防剖宫产术中卡前列素不良反应的效果

Hui-fen Liu, Dandan Yang, C. Hou
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摘要

目的探讨布托啡诺联合地塞米松预防剖宫产术中卡前列素不良反应的效果。方法对2017年1月至2019年1月在洛阳市妇幼保健院剖宫产的产妇120例进行筛查。采用随机数字表法将患者分为参照组和观察组,每组60例。对照组在子宫体内静脉注射丁丙诺啡,观察组在对照组基础上加用丁丙诺酚和地塞米松治疗。比较两组患者不良反应发生率。观察并比较两组患者术前、子宫体注射后10分钟、手术结束后的镇静评分。记录两组妇女术前、子宫体注射后40分钟及术后血流动力学指标水平。结果与对照组比较,观察组患者呕吐、恶心、胸闷、面潮红、高血压、寒战、心动过速等不良反应发生率均有显著下降趋势(P < 0.05)。子宫体注射后10 min,对照组镇静评分明显下降,观察组镇静评分明显上升(P < 0.05)。子宫体注射后40 min,两组患者心率、平均动脉压、呼吸频率均显著升高,但观察组升高幅度低于对照组(P<0.05)。结论布地诺联合地塞米松预防剖宫产术中卡前列素不良反应的临床效果理想,可有效缓解产妇的各种不适,减少各种不良反应的发生。关键词:丁托啡酚;地塞米松;剖腹产;Carprostol
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of butorphanol combined with dexamethasone on prevention of adverse reactions of carprost in cesarean section
Objective To discuss the effect of butorphanol combined with dexamethasone in preventing adverse reactions of carprost in cesarean section. Methods A total of 120 women who underwent cesarean delivery in Luoyang Maternal and Child Health Hospital from January 2017 to January 2019 were screened. The patients were divided into reference group and observation group by random number table method, 60 cases in each group. The reference group was given intravenous injection of buprenorphine in uterine body, the observation group was treated with butorphanol and dexamethasone on the basis of the control group. The incidences of adverse reactions in the two groups were compared. The sedation scores of the two groups of women were observed and compared before operation, 10 minutes after uterine body injection, and after completion of operation. The hemodynamic index levels of the two groups of women were recorded before operation, 40 minutes after uterine body injection, and after operation. Results Compared with reference group, the incidence of adverse reactions such as vomiting, nausea, chest tightness, facial flushing, hypertension, chills and tachycardia in the observation group showed a significant downward trend(P 0.05). Ten minutes after uterine body injection, the sedation score of control group showed a significant downward trend, while that of observation group showed a significant upward trend (P 0.05). Forty minutes after uterine body injection, the heart rate, mean arterial pressure and respiratory rate of the two groups were significantly increased, but the increasing range of observation group was lower than that of control group (P<0.05). Conclusions The clinical effect of budesonol combined with dexamethasone in preventing adverse reactions of carprost in cesarean section is ideal, which can effectively alleviate various discomforts of maternal and reduce the incidence of various adverse reactions. Key words: Butorphanol; Dexamethasone; Cesarean section; Carprostol
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