{"title":"平衡稳态自由进动成像方法的心肌血氧水平相关磁共振成像","authors":"R. Dharmakumar, S. Tsaftaris, Debiao Li","doi":"10.2174/1874347101206010031","DOIUrl":null,"url":null,"abstract":"The current state of myocardial Blood-Oxygen-Level-Dependent (BOLD) MRI with balanced steady-state free precession (SSFP) approaches is reviewed. Initial studies forming the basis for SSFP-based detection of oxygenation changes beginning with whole blood studies, progressing through controlled studies that consider microcirculatory changes in oxygenation in skeletal muscle and kidney, culminating in basic myocardial studies are outlined. The theoretical basis to observe signal changes and the mechanisms that facilitate such observations are elucidated. Methods to overcome limitations in sensitivity are described.","PeriodicalId":90366,"journal":{"name":"The open medical imaging journal","volume":"22 1","pages":"31-38"},"PeriodicalIF":0.0000,"publicationDate":"2012-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Myocardial Blood-Oxygen-Level-Dependent Magnetic Resonance Imaging with Balanced Steady-State Free Precession Imaging Approaches\",\"authors\":\"R. Dharmakumar, S. Tsaftaris, Debiao Li\",\"doi\":\"10.2174/1874347101206010031\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The current state of myocardial Blood-Oxygen-Level-Dependent (BOLD) MRI with balanced steady-state free precession (SSFP) approaches is reviewed. Initial studies forming the basis for SSFP-based detection of oxygenation changes beginning with whole blood studies, progressing through controlled studies that consider microcirculatory changes in oxygenation in skeletal muscle and kidney, culminating in basic myocardial studies are outlined. The theoretical basis to observe signal changes and the mechanisms that facilitate such observations are elucidated. Methods to overcome limitations in sensitivity are described.\",\"PeriodicalId\":90366,\"journal\":{\"name\":\"The open medical imaging journal\",\"volume\":\"22 1\",\"pages\":\"31-38\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-04-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The open medical imaging journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874347101206010031\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The open medical imaging journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874347101206010031","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Myocardial Blood-Oxygen-Level-Dependent Magnetic Resonance Imaging with Balanced Steady-State Free Precession Imaging Approaches
The current state of myocardial Blood-Oxygen-Level-Dependent (BOLD) MRI with balanced steady-state free precession (SSFP) approaches is reviewed. Initial studies forming the basis for SSFP-based detection of oxygenation changes beginning with whole blood studies, progressing through controlled studies that consider microcirculatory changes in oxygenation in skeletal muscle and kidney, culminating in basic myocardial studies are outlined. The theoretical basis to observe signal changes and the mechanisms that facilitate such observations are elucidated. Methods to overcome limitations in sensitivity are described.
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