人类蛔虫病,宿主和寄生虫之间进化上复杂的关系

M. Baldi, Norberto Baldi
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引用次数: 0

摘要

蛔虫病是一种使人衰弱的寄生虫病,已严重损害了数十万人的健康,特别是在发展中国家。缺乏适当的寄生虫预防与免疫疾病风险增加有关,这主要是在这种寄生虫流行率很低的发达国家面临的挑战。寄生虫能够在人类宿主中定居并建立自己的进化关系和机制尚未解开。此外,宿主消灭或控制寄生虫的免疫反应机制尚不完全清楚。了解这些免疫机制(近似值)将有助于为与寄生虫病的积极影响有关的疾病建立更好的医疗方法,从而也避免寄生虫病本身的不良影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ascariasis humana, una relación evolutivamente compleja entre el huésped y el parásito
Ascariasis is a debilitating parasitic disease that has decimated the health of hundreds of thousands of human beings, especially in developing countries. The lack of adequate prophylaxis of the parasite associated with an increased risk of immunological disease is a challenge mainly in developed countries where the prevalence of this parasite is very low. The evolutionary relationship and mechanisms by which the parasite was able to colonize and establish itself in human hosts have not yet been unraveled. In addition, the host immune response mechanisms to eliminate or control the parasite are not fully understood. Understanding these immunological mechanisms (proximates) will allow establishing better medical treatments for diseases related to the positive effects of parasitosis, thus also avoiding the undesirable effects of the parasitosis itself.
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