医护人员接种(Sinovac-CoronaVac)后抗体水平的评价

Hakan Erdogan, F. Pehlivanoğlu, G. Şengöz, Feride Velaei̇
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引用次数: 1

摘要

目的:本研究旨在评估灭活SARS-COV-2疫苗(Sinovac-CoronaVac)的有效性,该疫苗于2021年1月14日首次在土耳其的卫生保健专业人员中使用。方法:将无COVID-19病史、PCR检测阳性或无慢性疾病的医护人员纳入研究。两剂冠状病毒疫苗接种后1个月和6个月,用西门子SARS-CoV-2 IgG (sCOVG)试剂盒检测S1 RBD抗原抗体水平。结果:本研究共纳入108名卫生专业人员,其中女性35人,男性73人。参与者的平均年龄为37.5±10.7岁。共有103人(95.3%)抗体阳性,5人(4.6%)在第二次接种后抗体阴性。在第二次接种疫苗后,11名(10.1%)参与者被诊断出患有COVID-19。与第一个月相比,第6个月的抗体值显著下降(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Antibody Levels After Vaccination (Sinovac-CoronaVac) in Healthcare Workers
Objectives: This study aims to evaluate the effectiveness of the inactivated SARS-COV-2 vaccine (Sinovac-CoronaVac), first administered to healthcare professionals in Turkey on January 14, 2021. Methods: Healthcare professionals without a history of COVID-19, PCR test positivity, or chronic disease were included in the study. The antibody levels for S1 RBD antigen were measured with the Siemens SARS-CoV-2 IgG (sCOVG) kit one month and six months after the two-dose CoronaVac vaccine. Results: A total of 108 health professionals, 35 women and 73 men, were included in this study. The mean age of the participants was 37.5 ± 10.7 years. A total of 103 (95.3%) individuals had positive antibody values, and five (4.6%) had negative values after the second vaccination. After the second vaccine dose, 11 (10.1%) participants were diagnosed with COVID-19. There was a significant decrease in antibody values in the sixth month compared to the first month (p
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