巴西大西洋森林36种植物提取物的抑菌活性分析

Daniela Fernandes Ramos, Gilda Guimarães Leitão, Fernanda das Neves Costa, Lisandra Ferreira de Abreu, J. V. Villarreal, Suzana G. Leitão, Salvador Said Fernández, P. Silva
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引用次数: 23

摘要

采用REMA法测定了36种巴西大西洋森林植物提取物对结核分枝杆菌H37Rv和堪萨斯分枝杆菌的抑菌活性,浓度为100 ~ 0.20µg/mL。在36个提取物中,5个提取物对结核分枝杆菌有活性,其中3个提取物对堪萨斯分枝杆菌也有活性。对5种提取物进行抗结核分枝杆菌VERO细胞毒性试验。在浓度为100µg/mL时,鉴定出只有亲和仙子提取物无毒。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Análise da atividade antimicobacteriana de 36 extratos vegetais da Mata Atlântica brasileira
Thirty-six plant extracts from the brazilian Atlantic Forest were tested for their antimycobacterial activity against Mycobacterium tuberculosis H37Rv and M. kansasii, using the method REMA in seriate concentrations of 100 to 0.20 µg/mL. Among the thirty six extracts tested, five were active against M. tuberculosis, and three of these extracts also showed activity against M. kansasii. Cytotoxicity test with VERO cells was performed with the five extracts active against M. tuberculosis. Only the extract of Peschiera affinis was identified as non-toxic in the concentration of 100µg/mL.
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