尼日利亚克罗斯河州卡拉巴尔监狱囚犯和女性性工作者中慢性乙型肝炎感染的患病率和治疗资格

Itodo Sunday Ewaoche, I. Otu-Bassey, Margaret Nabagenyi, S. Utsalo
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引用次数: 4

摘要

乙型肝炎是当今日益严重的全球公共卫生问题。尽管公认的公共卫生当局对这些疾病加以控制,但这些疾病造成了医疗费用的大幅增加。迄今为止,尼日利亚大多数医院对慢性乙型肝炎治疗资格的事实和数字都有误解。因此,本横断面研究旨在评估Calabar市女性性工作者和有资格接受慢性乙型肝炎治疗的监狱囚犯的患病率并确定其比例。方法:采用高特异性、高敏感性的HBsAg试纸进行初步筛选。使用市售的酶联免疫吸附测定(ELIZA)试剂盒对反应性样品进行乙型肝炎标志物分析。采用化学和血液学分析仪进行LFT和FBC。结果:乙型肝炎病毒总感染率为5.72%。女性性工作者和监狱在押人员的患病率分别为8.16%和4.70%。相当大比例的囚犯长期感染病毒,根据APRI评分,他们有资格接受治疗。感染与使用未经消毒的纹身设备和注射药物有显著关系。结论:观察到的监狱内和妓院间HBV感染率较低,强调了对囚犯和性工作者人群进行疫苗接种的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and Eligibility for Treatment of Chronic Hepatitis B Infection among Prison Inmates and Female Sex Workers in Calabar, Cross River State, Nigeria
Hepatitis B is a growing worldwide public health issue today. The pathologies are responsible for considerable increase in healthcare expenses despite the widely recognized public health authority to keep then under control. Facts and figures have hitherto been misconstrued as regards Eligibility for treatment of chronic hepatitis B in most hospitals in Nigeria. This Cross-sectional study therefore is to evaluate the prevalence and determine the proportion of the female sex workers and prison inmates eligible for treatment of chronic hepatitis B in Calabar. Methods: Preliminary screening was done with a highly specific and sensitive HBsAg strip. Reactive samples were analyzed for hepatitis B markers using commercially available enzyme linked immunosorbent assay (ELIZA) kits. Chemistry and hematology analyzers were employed in carrying out LFT and FBC. Results: The overall prevalence of HBV was 5.72%. The prevalence rate of 8.16% and 4.70% were recorded for the female sex workers and prison inmates respectively. A significant proportion of the inmates were chronically living with the virus and are eligible for treatment going by the APRI scores. Infections were significantly associated with the use of unsterilized equipment for tattooing and injection drug use. Conclusion: The low observed intraprison and interbrothels prevalence of HBV underscore the need to vaccinate the inmates and sex workers population.
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