Luminiţa Fritea , Mihaela Tertiș , Alan Le Goff , Serge Cosnier , Robert Săndulescu , Cecilia Cristea
{"title":"基于石墨烯的多巴胺测定生物传感器☆","authors":"Luminiţa Fritea , Mihaela Tertiș , Alan Le Goff , Serge Cosnier , Robert Săndulescu , Cecilia Cristea","doi":"10.1016/j.protcy.2017.04.046","DOIUrl":null,"url":null,"abstract":"<div><p>Two different graphene/<em>β</em>-cyclodextrin (CD)-based biosensors were elaborated for dopamine (DA) determination starting from glassy carbon electrode (GCE). First one was obtained by modifying GCE with reduced graphene oxide (RGO), CD and tyrosinase (Tyr) immobilized with a polyethylenimine film. The second biosensor was obtained after the incorporation of RGO functionalized with a new synthesized pyrrole-<em>β</em>-CD derivative and Tyr in an electropolimerized poly-amphiphilic pyrrole film. These two new approaches have resulted in selective and sensitive determination of DA in pharmaceuticals and real human samples.</p></div>","PeriodicalId":101042,"journal":{"name":"Procedia Technology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.protcy.2017.04.046","citationCount":"9","resultStr":"{\"title\":\"Graphene-based Biosensors for Dopamine Determination\",\"authors\":\"Luminiţa Fritea , Mihaela Tertiș , Alan Le Goff , Serge Cosnier , Robert Săndulescu , Cecilia Cristea\",\"doi\":\"10.1016/j.protcy.2017.04.046\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Two different graphene/<em>β</em>-cyclodextrin (CD)-based biosensors were elaborated for dopamine (DA) determination starting from glassy carbon electrode (GCE). First one was obtained by modifying GCE with reduced graphene oxide (RGO), CD and tyrosinase (Tyr) immobilized with a polyethylenimine film. The second biosensor was obtained after the incorporation of RGO functionalized with a new synthesized pyrrole-<em>β</em>-CD derivative and Tyr in an electropolimerized poly-amphiphilic pyrrole film. These two new approaches have resulted in selective and sensitive determination of DA in pharmaceuticals and real human samples.</p></div>\",\"PeriodicalId\":101042,\"journal\":{\"name\":\"Procedia Technology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.protcy.2017.04.046\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Procedia Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212017317300476\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Procedia Technology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212017317300476","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Graphene-based Biosensors for Dopamine Determination
Two different graphene/β-cyclodextrin (CD)-based biosensors were elaborated for dopamine (DA) determination starting from glassy carbon electrode (GCE). First one was obtained by modifying GCE with reduced graphene oxide (RGO), CD and tyrosinase (Tyr) immobilized with a polyethylenimine film. The second biosensor was obtained after the incorporation of RGO functionalized with a new synthesized pyrrole-β-CD derivative and Tyr in an electropolimerized poly-amphiphilic pyrrole film. These two new approaches have resulted in selective and sensitive determination of DA in pharmaceuticals and real human samples.