由棒状颗粒组成的纯β-磷酸三钙颗粒的制备技术

M. Kamitakahara, R. Fujii, K. Ioku
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引用次数: 1

摘要

摘要:由棒状颗粒组成的球形β-磷酸三钙(β-TCP)颗粒有望成为生物可吸收的骨替代品。通过水热处理-TCP颗粒合成的缺钙羟基磷灰石(HA)颗粒,可以制备β-TCP颗粒。然而,当Ca/P摩尔比大于1.50时,根据水热条件的不同,热处理后不仅出现β-TCP相,还出现HA相。为了解决这一问题,在缺乏钙的HA颗粒中加入磷酸根离子或在起始成分中加入钱铁矿,使Ca/P摩尔比降低到1.50以下。我们发现,这些工艺可以有效地获得由棒状颗粒组成的纯-TCP颗粒,从而防止
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TECHNIQUES FOR PREPARING PURE β-TRICALCIUM PHOSPHATE GRANULES COMPOSED OF ROD-SHAPED PARTICLES
Hydrothermal, Phosphate Abstract: Spherical β-tricalcium phosphate (β-TCP) granules composed of rod-shaped particles are expected to be useful as bioresorbable bone substitutes. The β-TCP granules can be prepared by the heat treatment of Ca-deficient hydroxyapatite (HA) granules that are synthesized by hydrothermal treatment of  -TCP granules. However, when the Ca/P molar ratio of Ca-deficient HA becomes higher than 1.50, depending on the hydrothermal conditions, not only the β-TCP but also the HA phase appears following heat treatment. To resolve this problem, phosphate ions were incorporated into the Ca-deficient HA granules or monetite was added to decrease the Ca/P molar ratio to less than 1.50 in the starting composition. We revealed that these processes were effective in obtaining the pure  -TCP granules composed of rod-shaped particles and thus preventing
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