化学先驱罗素·马克的篝火故事

L. Kovács
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摘要

特立独行的美国化学家罗素·厄尔·马克(Russell Earl Marker, 1902-1995)以研究有机汞化合物的破碎、建立辛烷值的概念、研究碳氢化合物的重排以及探索旋光与有机化合物构型之间的关系而闻名。然而,他最大的成就是详细阐述了一类重要天然产物的种子分离和合成方法,从而帮助建立了一个基于类固醇药物化学的新产业。这位非凡之人的游牧生活表明,阻碍科学技术进步的巨大障碍是可以被意外发现、敏锐和奉献所克服的。然而,他从化学领域的过早退休是一个警告信号:每个科学家都是脆弱的,即使是最坚强的人,如果情况恶化,毅力也会消失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The campfire stories of Russell Marker, a pioneer of chemistry
The maverick American chemist Russell Earl Marker (1902–1995) is known for his studies on the fragmentation of organic mercury compounds, establishing the concept of the octane number, investigating the rearrangements of hydrocarbons and exploring the relationship between optical rotation and the configuration of organic compounds. His greatest achievement, however, is the elaboration of seminal isolation and synthetic methods of an important class of natural products that helped found a new industry, based on the pharmaceutical chemistry of steroids. The nomadic life of this extraordinary man demonstrates that the enormous obstacles thwarting the progress of science and technology can be surmounted by serendipity, acumen and devotion. However, his premature retirement from chemistry is a warning sign that every scientist is vulnerable and even the toughest man's perseverance can fade if the conditions worsen.
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