{"title":"几丁质合成酶:一个潜在的农业和治疗靶点","authors":"Ying Ye, Ze-Wei Guan, Xiao-Lei Zhu, Guang-Fu Yang","doi":"10.1016/j.aac.2022.11.007","DOIUrl":null,"url":null,"abstract":"<div><p>Chitin synthase (CHS) is a potential agricultural and therapeutic target. Recently, the crystal structures of CHS from <em>Phytophthora sojae</em> (<em>Ps</em>Chs1) and <em>Candida albicans</em> (<em>Ca</em>Chs2) were reported. Here, we highlight the achievements of <em>Ps</em>Chs1 and <em>Ca</em>Chs2, which would give some clues for design new inhibitor targeted upon CHS.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"1 2","pages":"Pages 87-88"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237122000284/pdfft?md5=ea05c9ee8de905ecf5a53220b47c8c22&pid=1-s2.0-S2773237122000284-main.pdf","citationCount":"3","resultStr":"{\"title\":\"Chitin synthase: A potential agricultural and therapeutic target\",\"authors\":\"Ying Ye, Ze-Wei Guan, Xiao-Lei Zhu, Guang-Fu Yang\",\"doi\":\"10.1016/j.aac.2022.11.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Chitin synthase (CHS) is a potential agricultural and therapeutic target. Recently, the crystal structures of CHS from <em>Phytophthora sojae</em> (<em>Ps</em>Chs1) and <em>Candida albicans</em> (<em>Ca</em>Chs2) were reported. Here, we highlight the achievements of <em>Ps</em>Chs1 and <em>Ca</em>Chs2, which would give some clues for design new inhibitor targeted upon CHS.</p></div>\",\"PeriodicalId\":100027,\"journal\":{\"name\":\"Advanced Agrochem\",\"volume\":\"1 2\",\"pages\":\"Pages 87-88\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2773237122000284/pdfft?md5=ea05c9ee8de905ecf5a53220b47c8c22&pid=1-s2.0-S2773237122000284-main.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Agrochem\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2773237122000284\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Agrochem","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2773237122000284","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Chitin synthase: A potential agricultural and therapeutic target
Chitin synthase (CHS) is a potential agricultural and therapeutic target. Recently, the crystal structures of CHS from Phytophthora sojae (PsChs1) and Candida albicans (CaChs2) were reported. Here, we highlight the achievements of PsChs1 and CaChs2, which would give some clues for design new inhibitor targeted upon CHS.
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