静息状态分析:ADHD受试者RS-fMRI数据集的模拟与验证

IF 1.2 4区地球科学 Q3 GEOCHEMISTRY & GEOPHYSICS

Periodico Di Mineralogia Pub Date : 2022-04-20 DOI:10.37896/pd91.4/91475

P. Prasanth, O. Maheswari

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引用次数: 0

摘要

功能磁共振成像(fMRI)数据分析的新方法最近被报道。有必要验证这些方法的可靠性，因为对结果的解释是主观的，因为fMRI数据中的基本事实是未知的。分析方法的验证需要了解数据的基本真相。模拟研究对于评估统计技术/分析方法的质量是必要的。各种研究机构和研究人员提供的模拟fMRI数据集大多是与事件/任务相关的。静息状态fMRI分析最近因其作为各种精神病理状况的生物标志物的能力而变得越来越重要。因此，有必要生成模拟数据来评估静息状态fMRI数据分析方法。本文提出了一种利用MATLAB模拟完整的四维静息状态fMRI数据的方法。模拟正常和ADHD受试者的fMRI数据，并与实时数据进行比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Resting State Analysis: Simulation and validation of RS-fMRI dataset for ADHD Subjects

Novel methods for the analysis of functional magnetic resonance imaging (fMRI) data are being reported lately. It is necessary to validate these methods for reliability as the interpretations of the results are subjective as the ground truth in the fMRI data is not known. Validation of analysis methods requires knowledge of the ground truth of the data. Simulation studies are necessary to assess the quality of the statistical technique/analysis methods. The simulated fMRI dataset provided by various research institutions and researchers are mostly event/task-related. Resting-state fMRI analysis has been gaining importance recently for its ability to be used as a biomarker for various psychopathological conditions. Hence there is a need to generate simulated data for evaluation of the resting-state fMRI data analysis methods. In this paper, a method is proposed to simulate a complete 4D resting-state fMRI data using MATLAB. The fMRI data is simulated for normal and ADHD subject and the results are compared with real time data.

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来源期刊

Periodico Di Mineralogia 地学-地球化学与地球物理

CiteScore

1.50

自引率

14.30%

发文量

审稿时长

>12 weeks

期刊介绍： Periodico di Mineralogia is an international peer-reviewed Open Access journal publishing Research Articles, Letters and Reviews in Mineralogy, Crystallography, Geochemistry, Ore Deposits, Petrology, Volcanology and applied topics on Environment, Archaeometry and Cultural Heritage. The journal aims at encouraging scientists to publish their experimental and theoretical results in as much detail as possible. Accordingly, there is no restriction on article length. Additional data may be hosted on the web sites as Supplementary Information. The journal does not have article submission and processing charges. Colour is free of charges both on line and printed and no Open Access fees are requested. Short publication time is assured. Periodico di Mineralogia is property of Sapienza Università di Roma and is published, both online and printed, three times a year.