电灼加硫酸锌联合治疗肛周尖锐湿疣合并HIV病例报告

IF 0.2 Q4 PHARMACOLOGY & PHARMACY
Lita Setyowatie, Rizky Devitasari
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引用次数: 0

摘要

简介:巨大尖锐湿疣(GCA)或布施克-洛温斯坦肿瘤是肛门生殖器疣的罕见变异。免疫损害条件与GCA的发展密切相关。GCA的治疗没有标准的治疗方法。它的大体积允许恶性转化和高复发率。病例介绍:男性,26岁,在过去的11个月抱怨在肛门疣。肿块越来越大,有时还出血。该患者1年前被诊断为HIV,并接受了常规抗逆转录病毒治疗(ARV)。肛周查体示茎状植物,色素减退,部分红斑,疣状表面,菜花状,多个,1.5x1.5x4 cm。乙酰白试验和组织病理学检查呈阳性,显示为尖锐湿疣。患者给予电灼联合硫酸锌5 ~ 10 mg/kg/天,疗程2个月。显著改善出现,GCA完全消失。结论:电灼和硫酸锌作为免疫调节剂可作为治疗GCA合并HIV的一种方法,因为它们可以协同作用,达到病变的消退和防止GCA复发的目的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case Report: Combination Therapy of Electrocautery and Zinc Sulfate in Perianal Giant Condylomata Acuminata with Human Immunodeficiency Virus (HIV)
Introduction: Giant Condylomata Acuminata (GCA) or Buschke-Lowenstein tumours are rare variations of anogenital warts. Immunocompromising conditions are closely related to the development of GCA. There is no standard therapy in the management of GCA. Its large size allows malignant transformation and high recurrence. Case Presentation: A male, 26 years old, with a complaint of wart in the anal in the last 11 months. The lump was getting bigger and sometimes bleed. The patient had been diagnosed with HIV 1 year ago and had received routine antiretroviral therapy (ARV). On physical examination of the perianal region showed stalked vegetation which was hypopigmented, partly erythema, verrucous surface, in the form of cauliflower, multiple, measuring 1.5x1.5x4 cm. A positive acetowhite test and histopathological examination showed condylomata acuminata. Patients were given combination electrocautery therapy and zinc sulfate 5-10 mg/kg/day for 2 months. Significant improvement appears and GCA disappears entirely. Conclusion: Electrocautery and zinc sulfate as an immunomodulator can be considered as a treatment of GCA with HIV because they can work synergistically to achieve resolution of the lesion and prevent recurrence of GCA.
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