Natural defense mechanisms in carp infected by bacterial aeromonosis and after treatment with the synbiotic drug “Enteronormin”

Aeromonosis of carp fish is one of the most common diseases of pond fish, which causes significant loss for fisheries: fish mortality is from 10 to 90 %. For fish treatment antibacterial drugs such as nitrofuran, antibiotics, feed antibiotics, as well as dyes are used . Despite the significant benefits of using antibiotics, it is now believed that overuse of any antibiotic substance over a period of time can lead to a local population of bacteria resistant to them. Therefore, probiotics have several advantages over existing vitamin and antibiotic drugs: they are technological in animal use; low toxic; cheap; simple and environmentally friendly production; high economic efficiency of application. Here are the results of studies of the influence of the synbiotic drug “Enteronormin” with iodine and selenium on the indices of nonspecific resistance to the organism of carp affected by bacterial aeromonosis. The research was conducted under the conditions of aquariums at the Lviv Research Station of the Institute of Fisheries of NAAS. The control group, which consisted of clinically healthy fish, received only 3 % starch suspension, the 1 st experimental group (E1) — aeromonosis affected carps who were given only 3 % starch suspension, the 2 nd experimental group (E2), which consisted of carps affected aeromonosis, through the probe within 7 days was administered the drug “Enteronormin” at the rate of 2 mg per 1 kg of fish weight in the composition of 3 % starch suspension. Before feeding for the carp drug was activated for 14–16 hours water enriched with Iodine and Selenium ions in the Iodis + Se form (TU U 15.7- 30631018-011:2011). Studies have shown that a disease associated with the bacterial form of aeromonosis has an immunosuppres sive effect on the body’s natural resistance. In particular, there was a decrease in the phagocytic activity of neutrophilic granulocytes and lysozyme activity of the blood serum against the background of an increase in the content of circulating immune complexes and phagocytic index. The rehabilitative effect of the enteronormin synbiotic drug on the investigated indices of cellular and humoral setions of nonspecific resistance of fish organisms affected by bacterial aeromonosis was ascertained.