经直肠超声引导分期前列腺活检术前检测局部晚期前列腺癌

A. Zisman, M. Herbert, S. Strauss, H. Manor, Dan Liebovici, A. Lindner
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引用次数: 1

摘要

治疗是为器官局限性前列腺癌患者保留的。前列腺癌的临床分期缺乏局部延伸的准确性。在常规前列腺六分仪活检(RSBs)之外进行的经直肠超声引导分期活检(TGSB)的结果被定义为当肿瘤细胞侵入前列腺外位点时呈阳性,因此肯定可以区分器官局限性疾病和局部晚期疾病。将77例RSB + TGSB手术与223例常规六分仪前列腺trgb进行比较。前列腺癌(CaP)分别检出24例(31%)和60例(27%)。在4例RSB + TGSB手术中,CaP出现局部延伸,因此不进行根治性前列腺切除术。在接受根治性前列腺切除术的7例患者中,有6例(86%)标本分析结果与术前TGSB结果一致。没有与分期活检相关的额外并发症。我们的结论是,TGSB是安全有效的,应该在根治性前列腺切除术的候选人中进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preoperative Detection of Locally Advanced Prostate Cancer by Using Transrectal Ultrasound‐Guided Staging Prostate Biopsy
Treatment for cure is reserved for patients with organ-confined prostate cancer. The clinical staging of prostate cancer lacks accuracy regarding local extension. The results of a transrectal ultrasound-guided staging biopsy (TGSB), performed in addition to routine sextant biopsies (RSBs) of the prostate, is defined as being positive when tumor cells are shown to invade extraprostatic loci and, thus, would certainly differentiate between organ-confined and locally advanced disease. Seventy-seven RSB + TGSB procedures were compared to 223 routine sextant prostate TRGBs. Prostate cancer (CaP) was detected in 24 patients (31%) and 60 patients (27%), respectively. In four RSB + TGSB procedures, local extension of CaP was depicted, and as a result radical prostatectomy was withheld. In six of seven patients undergoing radical prostatectomy (86%), the specimen analysis result was in agreement with the results of the preoperative TGSB. There were no extra complications associated with the performance of staging biopsies. We conclude that TGSB is safe and efficacious and that it should be performed in candidates for radical prostatectomy.
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