沙眼衣原体分子生物学检测技术研究进展

Q4 Health Professions

中华检验医学杂志 Pub Date : 2019-12-11 DOI:10.3760/CMA.J.ISSN.1009-9158.2019.12.017

J. Qiu, Likuan Xiong

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引用次数: 0

摘要

沙眼衣原体(CT)是临床上引起沙眼和性传播疾病的常见病原体。本文综述了分子生物学技术在CT检测中的进展及应用，主要包括实时PCR扩增试验、核酸等温扩增试验、PCR杂交、序列分析等，并比较了它们的优缺点。本文还简要介绍了CT即时检测技术的最新进展。关键词:沙眼衣原体;聚合酶链反应;核酸扩增技术;微阵列分析;多位点序列分型

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Recent advances of molecular biology technology in Chlamydia trachomatis detection

Chlamydia trachomatis (CT) is a prevalent pathogen clinically causing trachoma and sexually transmitted diseases. This review presents the progress and application of molecular biology techniques in CT detection according to different types of methodologies, mainly including real-time PCR amplification tests, nucleic acid isothermal amplification tests, PCR-hybridization, sequence analysis and compare their advantages and disadvantages. The recent developments of the point-of-care testing for CT are also briefly introduced in this paper. Key words: Chlamydia trachomatis; Polymerase chain reaction; Nucleic acid amplification techniques; Microarray analysis; Multilocus sequence typing

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来源期刊

中华检验医学杂志 Health Professions-Medical Laboratory Technology

CiteScore

0.40

自引率

0.00%

发文量

8037

期刊介绍：