Nicolas Gerritzen, Jana Ziob, Peter Brossart, Valentin S Schäfer
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引用次数: 0
摘要
嗜酸性粒细胞筋膜炎(EF,又称舒尔曼综合征)是一种不常见的结缔组织疾病,其特征是筋膜炎性增厚以及皮肤肿胀和变硬。它主要影响下肢。皮肤肿胀和硬化以及凹槽征是典型的临床表现。迄今为止,筋膜炎症和增厚的活检证据一直是诊断的金标准。文献中提到磁共振成像(MRI)是确诊的另一种方法。我们介绍了一例 54 岁德国男性的非对称性 EF 病例。他的右前臂出现疼痛性压痛,并伴有特征性凹槽征和右手活动受限。血细胞计数显示嗜酸性粒细胞增多,为0.57 G/L或9.6%(正常值:0.05-0.5 G/L和0.5-5.5%),ANA和ENA均为阴性。组织学确诊后,我们在核磁共振成像和超声波成像中发现了增厚的筋膜。在病程中,左外侧踝骨也出现了 EF。患者接受了泼尼松龙和甲氨蝶呤治疗。
[Imaging of eosinophilic fasciitis in ultrasound and MRI (magnetic resonance imaging): a case report].
Eosinophilic fasciitis (EF, also known as Shulman syndrome) is an uncommon connective tissue disease characterized by inflammatory thickening of the fasciae as well as swelling and hardening of the skin. It mostly affects the lower extremities. Swollen and indurated skin, together with the groove sign, are typical clinical signs. So far, biopsy evidence of inflammation and thickening of the fascia has been the gold standard for diagnosis. Magnetic resonance imaging (MRI) is mentioned in the literature as an alternative method for confirming the diagnosis. We present a case of asymmetric EF in a 54-year-old German male. He came with painful induration of the right forearm, with a characteristic groove sign and limitation of motion of the right hand. The blood count revealed eosinophilia with 0.57 G/l or 9.6% (normal: 0.05-0.5 G/l and 0.5-5.5%), ANA and ENA were negative. The diagnosis was confirmed histologically and we were able to detect a thickened fascia in MRI and ultrasound imaging. The EF also appeared in the left lateral malleolus during the course of the illness. Treatment was carried out with prednisolone and methotrexate.
期刊介绍:
International in coverage, Communications in Soil Science and Plant Analysis presents recent advances in plant and soil science, emphasizing on methods of analysis and interpretation of elemental content of soils and plants and plant nutrition. The Journal emphasizes agronomic and plantation crops with topics ranging from nutrition and methodology to precision agriculture, sustainable use of land and water resources, and increasing yield. Additional topics that are also covered in Communications in Soil Science and Plant Analysis : adverse growing conditions dealing with salinity and drought tolerance and their effects on crop yields soil chemistry; mineralogy; fertility and testing of soils; soil-crop nutrition; plant analysis; interpretation and correlation of soil tests and plant analyses; liming and fertilization of soils; and techniques for correcting deficiencies.
Scientists and crop consultants around the world benefit from the research published in Communications in Soil Science and Plant Analysis . The research can be utilized to further educational research programs and may also be applied to field operations, which are continuously changing and expanding based upon the peer reviewed research conducted and published in the journal.