自噬体生物发生膜的制备

Cell & developmental biology Pub Date : 2014-12-22 DOI:10.4172/2168-9296.1000E129

Livia Wilz, Liang Ge

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引用次数: 0

摘要

自噬是真核细胞用于细胞质成分大量周转以维持细胞稳态的基本策略。在机体水平上，自噬参与多种生理过程，如发育、代谢和免疫等。功能失调的自噬与许多人类疾病有关，包括癌症、神经变性、衰老、感染和代谢性疾病[1-3]。

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Preparing the Membrane for Autophagosome Biogenesis

Autophagy is a fundamental strategy eukaryotic cells employ for bulk turnover of cytoplasmic components to maintain cellular homeostasis. At the organismal level, autophagy is involved in a variety of physiological processes such as development, metabolism and immunity. Dysfunctional autophagy has been implicated in numerous human disorders including cancer, neurodegeneration, aging, infection and metabolic disease [1-3].

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Cell & developmental biology

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