单细胞测序技术进展

Qianli C Ma, Wenchao Wu, N. Ye, X. Wang, P. Yan, Heping Pan
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引用次数: 0

摘要

细胞是生命结构和生命活动的基本单位。由于细胞微环境复杂,发挥关键作用的成分含量相对较少,因此单细胞分析极具挑战性。近年来,单细胞测序技术得到了发展和成熟。单细胞测序可以揭示细胞的组成和生理多样性,并对现有的单细胞分离技术、单细胞全基因组扩增技术、单细胞全转录组扩增技术和单细胞转录组测序的原理和应用进行了总结和总结。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Progress in Single Cell Sequencing Technology
Cells are the basic unit of life structure and life activities. Because of the complex micro-environment of cells, the content of components that play a key role is relatively small, so single-cell analysis is extremely challenging. In recent years, single-cell sequencing technology has been developed and matured. Single-cell sequencing can reveal the composition and physiological diversity of cells, and the existing single-cell separation technology, single-cell whole genome amplification technology, single The principles and applications of cell whole transcriptome amplification technology and single cell transcriptome sequencing are summarized and summarized.
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