结直肠癌检测风险问卷的验证

D. P. Kulovskaya, Y. Shelygin, S. Frolov, S. Achkasov
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引用次数: 0

摘要

目的:编制并验证结直肠癌筛查问卷。患者与方法:697例无明显主诉的患者被纳入前瞻性研究。所有患者均行结肠镜检查和专项问卷调查。采用回归模型对确定问题的显著性水平进行分层。结果:结直肠癌39例(5.6%),结肠良性肿瘤283例(40.6%)。在ROC分析中,以23点为临界值将患者组分为结直肠肿瘤的高、低风险,敏感性为92.8%,特异性为39.2%。曲线下面积为0.724,预测值较好。结论:所编制的问卷对CRC高危患者的识别具有较好的预测能力,可纳入筛查方案模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validation of the risk questionnaire for colorectal cancer detection
AIM: to develop and validate of the colorectal cancer screening questionnaire.PATIENTS AND METHODS: six hundred ninety seven patients without any significant complaints were prospectively included in study. All patients underwent colonoscopy and specific questionnaire. Regression model was performed to stratificate significance level of definite questions.RESULTS: colorectal cancer (CRC) was diagnosed in 39 (5.6%) patients, benign colon neoplasms — in 283 (40.6%) patients. In the ROC analysis, a cut-off of 23 points divides the group of patients into high and low risk of colorectal neoplasms with a sensitivity of 92.8% and a specificity of 39.2%. The area under the curve was 0.724, which corresponds to the good predictive value.CONCLUSION: the developed questionnaire show good predictive power for high CRC risk patients identification, and can be included in the screening program model.
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