基因组春季同步可视化与IMAS

IF 1.3 Q4 ENGINEERING, BIOMEDICAL

Computer Methods in Biomechanics and Biomedical Engineering-Imaging and Visualization Pub Date : 2008-07-09 DOI:10.1109/MEDIVIS.2008.17

C. Shaw

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引用次数: 3

摘要

本文介绍了一种与交互式多基因组分析系统(IMAS)相结合的合成可视化分析工具。这种可视化分析工具使生物学家能够根据基因和基因簇的位置分析密切相关的生物体基因组之间的关系。生物学家从DNA序列开始使用IMAS，使用BLAST在相关序列中找到相似的基因，并使用这些相似性链接来创建增强的合成序列的节点链接图。我们将其称为Spring Synteny可视化，其目的是帮助生物学家发现物种间相似的基因排序关系。本文从计算、视觉设计和交互设计的角度描述了用于支持协同可视化的技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Genomic Spring-Synteny Visualization with IMAS

This paper presents a synteny visualization and analysis tool developed in connection with IMAS - the Interactive Multigenomic Analysis System. This visual analysis tool enables biologists to analyze the relationships among genomes of closely related organisms in terms of the locations of genes and clusters of genes. A biologist starts IMAS with the DNA sequence, uses BLAST to find similar genes in related sequences, and uses these similarity linkages to create an enhanced node-link diagram of syntenic sequences. We refer to this as Spring Synteny visualization, which is aimed at helping a biologist discover similar gene ordering relationships across species. The paper describes the techniques that are used to support synteny visualization, in terms of computation, visual design, and interaction design.

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来源期刊

Computer Methods in Biomechanics and Biomedical Engineering-Imaging and Visualization ENGINEERING, BIOMEDICAL-

CiteScore

2.80

自引率

6.20%

发文量

102

期刊介绍： Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization is an international journal whose main goals are to promote solutions of excellence for both imaging and visualization of biomedical data, and establish links among researchers, clinicians, the medical technology sector and end-users. The journal provides a comprehensive forum for discussion of the current state-of-the-art in the scientific fields related to imaging and visualization, including, but not limited to: Applications of Imaging and Visualization Computational Bio- imaging and Visualization Computer Aided Diagnosis, Surgery, Therapy and Treatment Data Processing and Analysis Devices for Imaging and Visualization Grid and High Performance Computing for Imaging and Visualization Human Perception in Imaging and Visualization Image Processing and Analysis Image-based Geometric Modelling Imaging and Visualization in Biomechanics Imaging and Visualization in Biomedical Engineering Medical Clinics Medical Imaging and Visualization Multi-modal Imaging and Visualization Multiscale Imaging and Visualization Scientific Visualization Software Development for Imaging and Visualization Telemedicine Systems and Applications Virtual Reality Visual Data Mining and Knowledge Discovery.