髂腹股沟上筋膜室阻滞对后外侧全髋关节置换术术后阿片类药物用量和功能恢复的影响:单盲随机对照试验。

IF 1.4 3区 心理学 Q3 EDUCATION, SPECIAL
Michele Carella, Florian Beck, Nicolas Piette, Sébastien Denys, William Kurth, Jean-Pierre Lecoq, Vincent L Bonhomme
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引用次数: 0

摘要

导言:后外侧入路全髋关节置换术(PLTHA)术后会出现中度至重度疼痛。髂腹股沟上筋膜室阻滞(SFICB)被认为是一种很有前景的镇痛技术:在这项前瞻性随机对照试验中,分析了 86 名计划采用脊髓麻醉进行 PLTHA 的患者的数据。患者被随机分为两组,每组 43 人。与对照组(C 组)相比,罗哌卡因组(R 组)使用 40 毫升 0.375% 罗哌卡因接受额外的 SFICB。作为主要终点,盲人观察员记录了术后 48 小时的吗啡总消耗量。次要终点是固定时间点(术后1小时和6小时,第1天和第2天的8:00、13:00和18:00)的0-10数字评分量表(静态和动态NRS)显示的静息和活动时的疼痛;第1天和第2天的行走表现;术后并发症,包括吗啡相关副作用或正压性不耐受症状,如头晕、恶心、视力模糊或血管迷走性晕厥:R组48小时的吗啡消耗量(毫克;中位数(IQR))明显低于C组(11(8.5-15.5)对26(21-33.5)):试验登记号:NCT04574479:试验注册号:NCT04574479。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of suprainguinal fascia iliaca compartment block on postoperative opioid consumption and functional recovery in posterolateral-approached total hip arthroplasty: a single-blind randomized controlled trial.

Introduction: Posterolateral-approached total hip arthroplasty (PLTHA) is followed by moderate to severe postoperative pain. Suprainguinal fascia iliaca compartment block (SFICB) has been proposed as a promising analgesia technique.

Methods: Data from 86 patients scheduled for PLTHA with spinal anesthesia were analyzed in this prospective randomized controlled trial. Patients were randomly divided into two groups of 43 patients each. As opposed to the control group (group C), ropivacaine group (group R) received additional SFICB using 40 mL of 0.375% ropivacaine. As primary endpoint, blind observers noted total morphine consumption at postoperative 48 hours. Secondary endpoints were pain at rest and mobilization on 0-10 Numeric Rating Scale (rest and dynamic NRS) at fixed time points (1 hour and 6 hours after surgery, and at day 1 and day 2 at 8:00, 13:00 and 18:00 hours), walking performance at day 1 and day 2; postoperative complications including morphine-related side effects or orthostatic intolerance symptoms such as dizziness, nausea, blurred vision or vasovagal syncope.

Results: A 48-hour morphine consumption (mg; median (IQR)) was significantly lower in group R than in group C (11 (8.5-15.5)) vs 26 (21-33.5), p<0001), as well as incidence of morphine-related side effects such as nausea at day 1 (p=0.04) and day 2 (p<0.01). Rest and dynamic NRS were globally significantly lower in group R than in group C (p<0.01). Group R showed less orthostatic intolerance at day 1 (p<0.001) and day 2 (p<0.01) and better functional walking performance at day 1 (<0.001) and day 2 (<0.001).

Discussion: In PLTHA, SFICB provides opioid sparing, improved postoperative pain control, and enhanced functional recovery.

Trial registration number: NCT04574479.

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来源期刊
CiteScore
4.90
自引率
14.30%
发文量
10
期刊介绍: ...offers sound, research-based principles of positive behavior support for use in school, home and community settings with people with challenges in behavioral adaptation. Regular features include empirical research; discussion, literature reviews, and conceptual papers; programs, practices, and innovations; forum; and media reviews.
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