某三级卫生保健中心献血者血清阳性率模式

B. Sethi, Sunil Kumar, K. Butola, J. Mishra, Yogesh Kumar
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引用次数: 13

摘要

虽然输血是一种拯救生命的手段,但它也有一定的风险。一般来说,输血相关不良事件分为感染性和非感染性。人类免疫缺陷病毒(HIV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和梅毒等输血传播感染因子是对接受者血液安全的最大威胁。为了评估疾病传播的规模和动态以及预防和控制,研究其血清阳性率是很重要的。我们的研究所迎合了喜马拉雅山山麓地区大量人口的需要,是血清学调查的重要中心。本研究旨在确定该地区某三级保健中心献血者中HIV、HBV、HCV和梅毒感染的血清阳性率。回顾性分析2007年1月至2011年12月(5年)符合献血者健康标准的献血者的医疗记录,对其进行HIV、HBS、HCV、梅毒和疟疾筛查。在收集的7884个单位中,83个(1.05%)单位HBsAg/anti-HCV Ab/anti-HIV Ab/anti-Treponemal Ab血清阳性,各2个单位显示HIV-HBV和HIV-HCV双重感染。血清HBsAg、抗hcv抗体、抗hiv抗体和抗梅毒抗体阳性率分别为0.63%、0.20%、0.19%和0.02%。即使实施了有效的预防战略,印度仍存在传染原传播的重大风险。确保充足和安全血液供应的努力应包括适当筛查和争取最佳使用血液及其制品。关键词:血清阳性率;艾滋病毒;乙型肝炎;丙型肝炎;梅毒;北阿坎德邦
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seroprevalence pattern among blood donors in a tertiary health care center
Although blood transfusion is a life-saving maneuver, it is associated with certain risks. In general, transfusion-related adverse events are categorized as infectious and noninfectious. Transfusion-transmissible infectious agents such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis are among the greatest threats to blood safety for the recipient. To assess the magnitude and dynamics of disease transmission and for its prevention and control, the study of its seroprevalence is important. Our institute, catering to the needs of a large population in the foothills of the Himalayas, represents an important center for serological surveys. This study aimed to determine the seroprevalence of HIV, HBV, HCV and syphilis infections among blood donors in a tertiary care center of this region. A retrospective analysis of medical records of blood donors who met the standard criteria for donor fitness were screened for HIV, HBS, HCV, Syphilis and Malaria, from January 2007 to December 2011 (5 years). Out of 7884 units collected, 83 (1.05%) units had seropositivity for HBsAg/anti-HCV Ab/anti-HIV Ab/anti-Treponemal Ab, 2 units each revealed dual infections with HIV-HBV and HIV-HCV. Seropositivity rates of HBsAg, anti-HCV Ab, anti-HIV Ab and anti-treponemal Ab were 0.63%, 0.20%, 0.19% and 0.02%, respectively. Even with the implementation of effective preventive strategies, there is significant risk of transmission of infectious agents in India. Efforts to ensure an adequate and safe blood supply should include proper screening and striving for optimal use of blood and its products. Keywords : Seroprevalence; HIV; Hepatitis B; Hepatitis C; Syphilis; Uttarakhand
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