高化学选择性Pd−C催化加氢脱氯导致苯胺的高效n -脱苯

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC

The Journal of Organic Chemistry Pub Date : 2009-06-17 DOI:10.1021/jo9007282

Chuanjie Cheng, Jianwei Sun, Lixin Xing, Jimin Xu, Xinyan Wang, Yuefei Hu

引用次数: 33

摘要

在1,1,2-三氯乙烷存在下，Pd?建立了苯胺的C催化n -脱苄基反应。该方法在协同催化体系中进行，并以实际定量收率直接得到结晶盐酸胺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Highly Chemoselective Pd−C Catalytic Hydrodechlorination Leading to the Highly Efficient N-Debenzylation of Benzylamines

查看原文本刊更多论文

Highly Chemoselective Pd−C Catalytic Hydrodechlorination Leading to the Highly Efficient N-Debenzylation of Benzylamines

In the presence of 1,1,2-trichloroethane, a novel procedure for the Pd?C catalytic N-debenzylation of benzylamines was established. The method proceeded in a synergistic catalytic system and directly gave the products as crystal amine hydrochlorides in practically quantitative yields.

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来源期刊

The Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.