Maha Mohammed Jasim Al Bayati, Sahar Abdul Baqi Sabti Al Dulaimi, Mayasah Abbas Abed
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引用次数: 0
摘要
目的:检测血清血管生成素-1水平作为早期妊娠漏流产的有效生物标志物。方法:纳入100例孕妇;采用酶联免疫吸附法检测两组患者血清血管生成素-1水平，分别为A组和B组。结果:与对照组相比，漏流产组患者血清血管生成素-1水平(771.12±165 VS 1381.12±340.36)显著降低，P值(0.001)。在研究分组中，漏流产与(体重指数、生育史)有相关性。结论:目前的研究表明，与匹配妊娠的正常存活宫内妊娠相比，漏流产孕妇血清血管生成素-1水平明显降低。
The usefulness of angiopoietin-1 as biomarker in missed abortion
Objective: To detect serum angiopoietin -1 level as effective biomarker for missed abortion in early pregnancy.
Methods: The study included 100 pregnant women; 50 pregnant women with missed abortion (group A) and 50 pregnant women with viable intrauterine pregnancy in first trimester (group B). Both groups were test for serum level of angiopoietin -1 using Enzyme linked immunosorbent assay technique.
Results: The mean serum angiopoietin -1 level is significantly decrease in missed abortion compare with control group women (771.12 ± 165 VS 1381.12 ± 340.36) respectively at P value (0.001). There was correlation between missed abortion and (body mass index, reproductive history) in groups of study.
Conclusion: The current study showed that serum levels of angiopoitin-1 are significantly decrease in pregnant women with missed abortion compared with its level in normal viable intrauterine pregnancy of matched gestation.
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