丁香酚的生物学评价、血液学研究及环境检测

B. M. Altahir, A. Al-Awadi, S. M. Shakir, O. Abdulazeez
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引用次数: 1

摘要

丁香酚存在于许多植物的精油中。它属于一类天然存在的酚类单萜类,化学上它是一个烯丙基链取代愈创木酚。对丁香酚化合物进行了一项研究,包括不同的研究。首先对包括血清、唾液和尿液在内的体液中丁香酚的含量进行了测定,发现尿液中丁香酚的浓度最高,其次是血清和唾液。第二个研究是血液学研究。在使用含有丁香酚的漱口水的志愿者身上完成了全血细胞计数分析在使用漱口水之前和之后完成。结果观察到轻微的阴性结果,并没有那么显著,这证实了严格的血液系统抵抗化合物的毒性或给予时间较短的事实。第三项研究包括通过对白化雄性白化雄性小鼠进行实验,对该化合物对动物身体组织的影响进行组织学研究。大鼠给药10天后出现副作用,皮肤出现黄斑,肝脏肿大。第四项研究是环境分析和该化合物对环境的影响。丁香酚在水中具有稳定性和持久性,在牙科医院污水主池中发现浓度为11 mg/L。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biological Assessment, Heamatological Study, and Environmental Detection of Eugenol
Eugenol is found in essential oils of many plants. It belongs to a class of naturally occurring phenolic monoterpenoids, chemically it is an allyl chain-substituted guaiacol. A study was conducted on the compound of Eugenol, which included different studies. The first study was the determination of eugenol in body fluid, which includes serum, saliva and urine has been found the highest concentration was in urine then serum and saliva. The second study was the hematological study. Complete blood count was accomplished on the volunteers alredy administrated with eugenol contained mouthwash the analysis was accomplished before and after the mouth wash use. The result observed a slightly negative results and was not that significant, which confirms the strict blood system to resist the toxicity of the compound or the fact that the time period of giving was short.The third study included a histological study on the effect of this compound on the tissues of the animal body by conducting experiments on albino male albino male mice. The side effects were found after 10 days of rat infusion, with yellow spots on the skin and hepatomegaly. The fourth study was the environmental analyses and the effect of this compound on the environment. The eugenol was stable and persistent in water and had found of 11 mg/L concentration in the main tank of wastewater for the dental hospital swage.
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