Osteoartropathies associated with hypoteriosis in endemic goiter in sheep in the Republic of Khakasia

The article discusses the issues of changes in the state of the musculoskeletal system, in particular the skeletal system, in ewes and lambs with thyroid pathologies with iodine deficiency, kept in the conditions of peasant farms in the Beisky district of the Republic of Khakassia. The results are obtained from 20 ewes and their lambs with severe thyroid hyperplasia, for the period from 2020 to 2021. In the study of sheep using clinical, biochemical and radiological methods of research, they turned to the clinical status of animals with details on the musculoskeletal system: the state of muscles, joints, bones. As a result of the research, it was found that system-wide deviations in the body of sheep with endemic goiter and hypothyroidism are caused by the complex effect of iodine deficiency, against the background of an increased content of fluorine, cobalt, calcium in animal feed and water, which is due to being in an ecologically unfavorable zone. Endemic goiter and hypothyroidism occurs in adult sheep in a latent form and is clinically expressed in their offspring. Clinical signs of hypothyroidism in lambs are expressed by the development of myxedema, the development of myopathies and osteoarthropathy, caused by disturbances in oxidative processes and thermogenesis in the body. X-ray signs of thyroid osteoarthropathies are expressed by a slowdown in osteogenesis, especially epiphyseal growth zones of the type of punctate dysplasia, more pronounced on the pelvic limbs, the presence of moderate osteoporosis with an elevated level of calcium in the blood. The established biochemical abnormalities in blood parameters are characterized by an increase in the level of liver enzymes: ALT, AST, alkaline phosphatase and are directly proportional to the severity of clinical signs and the degree of thyroid hyperplasia.