{"title":"[bmim][PF6]-水双相体系中环丙基吡唑杂合物的快速合成及生物学评价","authors":"P. C. Burde, A. Rahatgaonkar","doi":"10.14233/ajomc.2019.ajomc-p192","DOIUrl":null,"url":null,"abstract":"3-Cyclopropyl-5-(4-substituted)-1-phenyl-4,5-dihydro-1H-pyrazoles derived from corresponding\nchalcones were synthesized and evaluated for their biological activities. A convenient synthesis of a\nlibrary of these compounds in 1-butyl-3-methylimidazolium hexafluorophosphate-water biphasic system\nat ambient temperature has been accomplished. The ionic liquid, [bmim][PF6] and water which are\nimmiscible, has been easily recycled and reused after separation of the products without any noticeable\ndiminution in its activity.","PeriodicalId":8846,"journal":{"name":"Asian Journal of Organic & Medicinal Chemistry","volume":"16 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Facile Synthesis and Biological Evaluation of Cyclopropyl-Pyrazole\\nHybrids in [bmim][PF6]-Water Biphasic System as Antifungal Agents\",\"authors\":\"P. C. Burde, A. Rahatgaonkar\",\"doi\":\"10.14233/ajomc.2019.ajomc-p192\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"3-Cyclopropyl-5-(4-substituted)-1-phenyl-4,5-dihydro-1H-pyrazoles derived from corresponding\\nchalcones were synthesized and evaluated for their biological activities. A convenient synthesis of a\\nlibrary of these compounds in 1-butyl-3-methylimidazolium hexafluorophosphate-water biphasic system\\nat ambient temperature has been accomplished. The ionic liquid, [bmim][PF6] and water which are\\nimmiscible, has been easily recycled and reused after separation of the products without any noticeable\\ndiminution in its activity.\",\"PeriodicalId\":8846,\"journal\":{\"name\":\"Asian Journal of Organic & Medicinal Chemistry\",\"volume\":\"16 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-10-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Organic & Medicinal Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14233/ajomc.2019.ajomc-p192\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Organic & Medicinal Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14233/ajomc.2019.ajomc-p192","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Facile Synthesis and Biological Evaluation of Cyclopropyl-Pyrazole
Hybrids in [bmim][PF6]-Water Biphasic System as Antifungal Agents
3-Cyclopropyl-5-(4-substituted)-1-phenyl-4,5-dihydro-1H-pyrazoles derived from corresponding
chalcones were synthesized and evaluated for their biological activities. A convenient synthesis of a
library of these compounds in 1-butyl-3-methylimidazolium hexafluorophosphate-water biphasic system
at ambient temperature has been accomplished. The ionic liquid, [bmim][PF6] and water which are
immiscible, has been easily recycled and reused after separation of the products without any noticeable
diminution in its activity.
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