{"title":"使用克拉德宾治疗多发性硬化症:一篇图片文章","authors":"J. Stewert","doi":"10.37532/2041-6792.2021.11(1).31","DOIUrl":null,"url":null,"abstract":"Cladribine reaches the cell via proteins that hold nucleoside. Cladribine is activated within the cell by three subsequent phosphorylations, the first being deoxycytidine kinase. The enzyme 5'-nucleotidase (5'-NTase), active cladribine can be inactivated by dephosphorylation.","PeriodicalId":10369,"journal":{"name":"Clinical investigation","volume":"142 1","pages":"31-31"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Use of Cladribine for multiple sclerosis treatment: An image article\",\"authors\":\"J. Stewert\",\"doi\":\"10.37532/2041-6792.2021.11(1).31\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cladribine reaches the cell via proteins that hold nucleoside. Cladribine is activated within the cell by three subsequent phosphorylations, the first being deoxycytidine kinase. The enzyme 5'-nucleotidase (5'-NTase), active cladribine can be inactivated by dephosphorylation.\",\"PeriodicalId\":10369,\"journal\":{\"name\":\"Clinical investigation\",\"volume\":\"142 1\",\"pages\":\"31-31\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical investigation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37532/2041-6792.2021.11(1).31\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical investigation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37532/2041-6792.2021.11(1).31","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Use of Cladribine for multiple sclerosis treatment: An image article
Cladribine reaches the cell via proteins that hold nucleoside. Cladribine is activated within the cell by three subsequent phosphorylations, the first being deoxycytidine kinase. The enzyme 5'-nucleotidase (5'-NTase), active cladribine can be inactivated by dephosphorylation.
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