用分子治疗方法治疗乳腺癌的潜在活性化合物:文章复习

Alma Yunita Sari, Ellin Febrina
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引用次数: 0

摘要

乳腺癌是全世界妇女死亡的主要原因之一。乳腺癌可由物理、化学、环境因素引发,并可通过基因代代相传。因此,最近,人们集中研究使用药用植物作为治疗乳腺癌的一种选择,因为与其他化疗相比,它们的副作用很小。本文综述了利用分子锚定方法在计算机研究中发现的具有抗癌潜力的药用植物及其活性化合物。撰写本文的方法是在PubMed、Cochrane和Google Scholar等数据库中,使用关键词乳腺癌、分子对接、草药植物、抗癌,对过去五年国内外的文献进行综述。在计算机研究中,作为癌症治疗有很大潜力的草药植物包括33种具有不同活性化合物和蛋白质靶点的草药植物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Potensi Senyawa Aktif Tanaman Herbal untuk Pengobatan Kanker Payudara dengan Metode Penambatan Molekuler: Review Artikel
Breast cancer is one of the leading causes of death in women worldwide. Breast cancer can be triggered due to physical, chemical, environmental factors and can be passed down from generation to generation through genetics. Therefore, recently, studies have been intensively conducted on the use of medicinal plants for the treatment of breast cancer as an alternative because they have minimal side effects compared to other chemotherapy. This review aims to describe medicinal plants and their active compounds that have the potential as anticancer therapy which has been carried out in silico studies with molecular anchoring methods. The method used in writing this article is a literature review both nationally and internationally over the last five years using the keywords breast cancer, molecular docking, herbal plants, anticancer, in databases such as PubMed, Cochrane, and Google Scholar. Herbal plants in in silico research that have high potential for further research as cancer therapy include 33 herbal plants with different active compounds and protein targets.
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