曲恩汀增加威尔逊氏病患者粪铜排泄1例报告

Shozo Ishikawa, Shozo Nomoto, Kunihiro Yoshida, Takahiko Tokuda, Shu-ichi Ikeda
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引用次数: 0

摘要

在连续7天内进行了一项铜平衡研究,当一名威尔逊病患者进行低铜饮食,每天服用1500毫克的曲安汀。平均铜摄入量为944 μg/d,尿铜排泄量为503 μg/d,粪铜排泄量为922 μg/d;因此,曲恩汀每天可减少体内铜约500 μg。我们提供的直接证据表明,曲恩汀可能通过促进尿液和粪便的排泄来维持铜平衡,粪便中有大量的脱铜。J. Trace Elem。中华医学杂志,2001,14(4):555 - 557。©2001 Wiley-Liss, Inc。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Trientine increases fecal copper excretion in Wilson's disease: A case report

A copper balance study was performed during the successive 7 days when a patient with Wilson's disease went on a low-copper diet and was taking 1500 mg of trientine daily. The average copper intake was 944 μg/day, urine copper excretion was 503 μg/day, fecal copper excretion was 922 μg/day; therefore, trientine reduced body copper about 500 μg per day. We provide direct evidence that trientine maintains copper balance probably by enhancing both the urinary and fecal excretion, with a larger amount decoppered in the feces. J. Trace Elem. Exp. Med. 14:405–407, 2001. © 2001 Wiley-Liss, Inc.

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