{"title":"曲恩汀增加威尔逊氏病患者粪铜排泄1例报告","authors":"Shozo Ishikawa, Shozo Nomoto, Kunihiro Yoshida, Takahiko Tokuda, Shu-ichi Ikeda","doi":"10.1002/jtra.1051","DOIUrl":null,"url":null,"abstract":"<p>A copper balance study was performed during the successive 7 days when a patient with Wilson's disease went on a low-copper diet and was taking 1500 mg of trientine daily. The average copper intake was 944 μg/day, urine copper excretion was 503 μg/day, fecal copper excretion was 922 μg/day; therefore, trientine reduced body copper about 500 μg per day. We provide direct evidence that trientine maintains copper balance probably by enhancing both the urinary and fecal excretion, with a larger amount decoppered in the feces. J. Trace Elem. Exp. Med. 14:405–407, 2001. © 2001 Wiley-Liss, Inc.</p>","PeriodicalId":101243,"journal":{"name":"The Journal of Trace Elements in Experimental Medicine","volume":"14 4","pages":"405-407"},"PeriodicalIF":0.0000,"publicationDate":"2001-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/jtra.1051","citationCount":"0","resultStr":"{\"title\":\"Trientine increases fecal copper excretion in Wilson's disease: A case report\",\"authors\":\"Shozo Ishikawa, Shozo Nomoto, Kunihiro Yoshida, Takahiko Tokuda, Shu-ichi Ikeda\",\"doi\":\"10.1002/jtra.1051\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A copper balance study was performed during the successive 7 days when a patient with Wilson's disease went on a low-copper diet and was taking 1500 mg of trientine daily. The average copper intake was 944 μg/day, urine copper excretion was 503 μg/day, fecal copper excretion was 922 μg/day; therefore, trientine reduced body copper about 500 μg per day. We provide direct evidence that trientine maintains copper balance probably by enhancing both the urinary and fecal excretion, with a larger amount decoppered in the feces. J. Trace Elem. Exp. Med. 14:405–407, 2001. © 2001 Wiley-Liss, Inc.</p>\",\"PeriodicalId\":101243,\"journal\":{\"name\":\"The Journal of Trace Elements in Experimental Medicine\",\"volume\":\"14 4\",\"pages\":\"405-407\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2001-10-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1002/jtra.1051\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Trace Elements in Experimental Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jtra.1051\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Trace Elements in Experimental Medicine","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jtra.1051","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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