伊斯兰堡郊区三级保健中脂肪肝患者胆结石的发生率

Iftikhar Ahmed, Arslan Zahid, Nauman Mustafa, Iram Iqbal, Asma Bibi, Fauzia Rashid, Shabir Rana, Tariq Nawaz
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摘要

背景:胆结石病和非酒精性脂肪性肝病(NAFLD)具有共同的病因途径。本研究的目的是确定在我院接受腹部超声检查的患者胆结石和非酒精性脂肪性肝病(NAFLD)的频率,并比较有NAFLD和无NAFLD患者胆结石疾病的频率。方法:本横断面研究于2020年1月至2020年12月在伊斯兰堡HBS总医院进行。在医院门诊部接受常规超声检查的患者被纳入研究。有急诊超声检查、有酒精摄入史、有慢性肝病史和怀孕的患者被排除在研究之外。数据分析采用Microsoft Excel 2016和IBM SPSS 22。结果:共纳入689例患者,男女比例为3:1。平均年龄40.65±15.610岁。胆结石患病率为20.9%,NAFLD患病率为27.6%。与非NAFLD患者相比,NAFLD患者有胆结石的比例更高(分别为24.2%和19.6%),但总体数据没有达到统计学意义。与未患NAFLD的年轻患者相比,患有胆结石的年轻患者数量有统计学意义(50% vs 6%, p<0.001)。NAFLD患者和胆结石患者的平均年龄更大。结论:NAFLD患者胆囊结石发生率高于非NAFLD患者。关键词:胆石症,脂肪肝,胆结石,非酒精性,超声
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frequency of Gallstones in Fatty Liver disease in a Tertiary Care of Suburban Islamabad
Background: Gallstone disease and Non-Alcoholic Fatty Liver Disease (NAFLD) share common etiological pathways. The objective of this study was to determine the frequency of Gallstones and Non-Alcoholic Fatty Liver disease (NAFLD) in patients undergoing abdominal ultrasounds in our hospital and to compare the frequency of Gallstone disease in patients with NAFLD and without NAFLD. Methodology: This cross-sectional study was carried out at HBS General Hospital, Islamabad from January 2020 till December 2020. Patients undergoing routine ultrasounds in the out-patient department of the hospital were included in the study. Patients having Emergency Ultrasounds, history of Alcohol intake, history of chronic liver disease and pregnant patients were excluded from the study.  Data was analysed using Microsoft Excel 2016 and IBM SPSS 22. Results: A total of 689 patients were included with a 3:1 Female to Male ratio. Mean Age was 40.65± 15.610 years. The prevalence of Gallstone disease was found to be 20.9% while that of NAFLD 27.6%. A higher percentage of patients with NAFLD had Gallstones as compared to those who did not have NAFLD (24.2% vs 19.6% respectively) however for overall data, statistical significance was not reached. A statistically significant greater number of young patients with NAFLD had Gallstones as compared to those who did not have NAFLD (50% vs 6%, p<0.001). Mean age was greater in patients who had NAFLD as well as those having Gallstones. Conclusion: The frequency of Gallstones was greater in patients with NAFLD as compared to those without NAFLD. Keywords: Cholelithiasis, Fatty Liver Disease,  Gallstones, Non-Alcoholic, Ultrasonogram  
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