静电纺丝法合成负载长效药理学物质的高分子(自消失)纳米医用贴片

IF 4.9 Q2 NANOSCIENCE & NANOTECHNOLOGY
Alia Hindi, Mohammad Yahia Masri, S. Hardcastle, M. Batal
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引用次数: 0

摘要

采用合成聚合物PVA和PVP共旋法制备载长效药物的纳米聚合物(自消失)医用贴片,每种聚合物的共旋率为10%W,添加不同的药用物质双氯芬酸去乙胺、庆大霉素,浓度为5%w(每种物质分别)。并通过扫描电镜(SEM)和X射线衍射(XRD)研究制备的样品的形态结构,然后将其转化为医用胶粘剂形式,然后直接在人的手上进行测试,因为它已经证明了其直接将药物传递到患处的有效性。它的生产不需要庞大的工业设备,因此非常容易使用,医学上安全且经济。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis of Polymeric (Self-Disappearing) Nano Medical Patches Loaded with a Long-Acting Pharmacological Substance by Electrospinning Method
Nano-polymer (self-disappearing) medical patches loaded with a long-acting drug were manufactured by cospinning method of synthetic polymers PVA and PVP at a rate of 10%W for each polymer and with the addition different medicinal substances, namely diclofenac de ethylamine, gentamicin, in concentration 5%w (each substance separately). And studding the morphological structure of the prepared samples by scanning electron microscope (SEM) and X- Ray diffraction (XRD), then converted into a medical adhesive form, and then tested on the human hand directly, as it has proven its effectiveness in delivering the drug to the affected area directly. It is very easy to use, medically safe and economic, as it does not need huge industrial equipment for its production.
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来源期刊
Nanotechnology, Science and Applications
Nanotechnology, Science and Applications NANOSCIENCE & NANOTECHNOLOGY-
CiteScore
11.70
自引率
0.00%
发文量
3
审稿时长
16 weeks
期刊介绍: Nanotechnology, Science and Applications is an international, peer-reviewed, Open Access journal that focuses on the science of nanotechnology in a wide range of industrial and academic applications. The journal is characterized by the rapid reporting of reviews, original research, and application studies across all sectors, including engineering, optics, bio-medicine, cosmetics, textiles, resource sustainability and science. Applied research into nano-materials, particles, nano-structures and fabrication, diagnostics and analytics, drug delivery and toxicology constitute the primary direction of the journal.
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