Modeling of Cerebral Anoxia of Respiratory Genesis in Rats

Anoxia as an extreme degree of acute oxygen starvation of the brain cells, regardless of the causes, leads to its greatest damage. As a result of using a new model of cerebral anoxia we have established disturbances in the parietal cortex of the rat brain, manifested by changes in the size, shape of neurons, the degree of their chromatophilia. This indicates the possibility of using the method of modeling anoxia by tracheal compression to study acute cerebral oxygen deficiency. It provides an opportunity to assess visually the dynamics of neuronal changes under anoxia without shutting down the cerebral circulation. It may be of value for further study of the consequences of disorders in the brain arising from respiratory pathology and external causes accompanied by asphyxia.