用于自主神经系统研究的心血管系统Bond图建模

V. Le Rolle , A. Hernandez , P.-Y. Richard , J. Buisson , G. Carrault
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引用次数: 1

摘要

提出了一个由心室、循环系统和心脏活动调节组成的心血管系统模型。心室模型包括对心脏收缩过程中发生的机电现象的描述。它解释了心脏的整体行为,并与循环模型相结合。整个心血管系统受到一种调节模式的影响。事实上,心血管系统是由自主神经系统(ANS)调节的。在这项工作中,只考虑了血压的短期调节(压力反射)的影响。该模型允许模拟ANS的各种生理测试,如倾斜测试或Valsalva manœuvre。这些检查通常用于检测病人的某些病理(如晕厥)。但是,由于SCV的复杂性,对所获得的信号(血压、心率)的解释往往很困难。借助该模型,可以更好地理解SCV和ANS之间的相互作用;并对倾斜测试和Valsalva manœuvre获得的信号进行生理解释。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modélisation Bond Graph du système cardiovasculaire pour l'étude du système nerveux autonome

A model of the cardiovascular system (CSV) that consists of the ventricle, the circulatory system and the regulation of the cardiac action is presented. The model of the ventricle includes a description of the electromechanical phenomena occurring during cardiac contraction. It explains the global behaviour of the heart and is coupled with a model of the circulation. The whole cardiovascular system is under the influence of a regulation model. In fact, the cardiovascular system is regulated by the Autonomic Nervous System (ANS). In this work, only the influence of the short-term regulation of blood pressure (the baroreflex) is considered. The model allows the simulation of various physiological tests of the ANS, like the tilt test or the Valsalva manœuvre. These tests are usually used with patients to detect some pathology (syncope for example). But the interpretation of the signals obtained (blood pressure, heart rate) is often difficult because of the complexity of the SCV. It is then possible to improve the comprehension of the interaction between the SCV and the ANS thanks to the model; and to give a physiological interpretation of the signals obtained with the tilt test and the Valsalva manœuvre.

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