{"title":"新基与蓝鸟生物合作推进CAR - t细胞癌症治疗","authors":"Heather Cartwright","doi":"10.3833/pdr.v2013i4.1919","DOIUrl":null,"url":null,"abstract":"Celgene has partnered with Bluebird bio to discover, develop and commercialise novel disease-altering gene therapies in oncology that utilise a patient’s own genetically modified T-cells, known as chimeric antigen receptor (CAR) T-cells, to target and destroy cancer cells selectively. Celgene has the option to license collaboration products on completion of each Phase I study; bluebird will be responsible for R&D up until this point. In a separate deal, Celgene has also formed a collaboration with the Center for Cell and Gene Therapy in the CAR T-cell field.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"30 2 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2013-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Celgene Partners with Bluebird Bio to Advance CAR T-Cell Cancer Therapies\",\"authors\":\"Heather Cartwright\",\"doi\":\"10.3833/pdr.v2013i4.1919\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Celgene has partnered with Bluebird bio to discover, develop and commercialise novel disease-altering gene therapies in oncology that utilise a patient’s own genetically modified T-cells, known as chimeric antigen receptor (CAR) T-cells, to target and destroy cancer cells selectively. Celgene has the option to license collaboration products on completion of each Phase I study; bluebird will be responsible for R&D up until this point. In a separate deal, Celgene has also formed a collaboration with the Center for Cell and Gene Therapy in the CAR T-cell field.\",\"PeriodicalId\":19951,\"journal\":{\"name\":\"Pharmadeals Review\",\"volume\":\"30 2 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-08-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmadeals Review\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3833/pdr.v2013i4.1919\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmadeals Review","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3833/pdr.v2013i4.1919","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
Celgene与Bluebird bio合作,发现、开发并商业化肿瘤领域改变疾病的新型基因疗法,这种疗法利用患者自身的基因修饰t细胞,即嵌合抗原受体(CAR) t细胞,选择性地靶向并摧毁癌细胞。Celgene可以选择在完成每个I期研究后授权合作产品;到目前为止,蓝鸟将负责研发。在另一项单独的交易中,Celgene还与CAR - t细胞领域的细胞和基因治疗中心(Center for Cell and Gene Therapy)达成了合作。
Celgene Partners with Bluebird Bio to Advance CAR T-Cell Cancer Therapies
Celgene has partnered with Bluebird bio to discover, develop and commercialise novel disease-altering gene therapies in oncology that utilise a patient’s own genetically modified T-cells, known as chimeric antigen receptor (CAR) T-cells, to target and destroy cancer cells selectively. Celgene has the option to license collaboration products on completion of each Phase I study; bluebird will be responsible for R&D up until this point. In a separate deal, Celgene has also formed a collaboration with the Center for Cell and Gene Therapy in the CAR T-cell field.