Dramatic Recovery of a Patient With Wernicke Encephalopathy Presenting With the Lesion of the Corpus Callosum

In this report, I present a rare patient of Wernicke encephalopathy (WE) with a callosal lesion on magnetic resonance imaging at whom a dramatic clinical recovery was achieved by parenteral thiamine therapy. Based on the presentation of this patient, first, I suggest that the awareness of WE among clinicians should be further increased. Second, I re-emphasize the importance of initiation of parenteral thiamine treatments in clinical suspicion of WE which may provide dramatic responses even in patients with atypical lesion sites as in our patient. Future reports including outcomes of a larger number of cases with distinct neuroimaging signs may provide a better understanding of the real clinical burden of the disease as well as unknown aspects of WE. J Neurol Res. 2020;10(1):17-19 doi: https://doi.org/10.14740/jnr559