醛二胺的合成研究:第一部分。多取代苯胺苯甲醛醛胺的合成、表征及生物活性研究

C. J. Patil, M. Patil, M. C. Patil
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引用次数: 1

摘要

以芳香族醛苯甲醛为原料,与苯胺、2-氯苯胺、3-氯苯胺、4-氯苯胺、2-硝基苯胺、3-硝基苯胺和4-硝基苯胺等7种不同的芳香族胺进行常规缩合反应,以中高收率和高纯度合成了一系列醛胺I ~ VII。采用薄层色谱法对反应过程进行了监测和分析。对所得产物进行了颜色、物理常数、薄层色谱、元素分析和光谱(UV-Vis和FTIR)表征。合成的醛二胺具有体外生物活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Studies on Synthesis of Aldimines: Part-I. Synthesis, Characterization and Biological Activity of Aldimines from Benzaldehyde with variedly substituted anilines
A conventional condensation reaction of an aromatic aldehyde, Benzaldehyde with seven different aromatic amines viz. Aniline, 2-Choro-aniline, 3-Choro-aniline, 4-Choro-aniline, 2-Nitro-aniline, 3-Nitro-aniline and 4-Nitro-aniline and reacted efficiently to synthesize a series of Aldmines, I to VII, in moderate to high yield and high purity. The reaction was monitored and the products were analyzed by employing the TLC technique. All the products obtained were characterized by their colour, physical constant, TLC, elemental analysis and spectral (UV-Vis and FTIR) method. The synthesized Aldimines were subjected to in vitro biological activity.
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