高流量鼻氧治疗在土耳其成人重症监护病房的使用:多中心前瞻性研究

F. Yıldırım, S. Ocal, Ebru Ortaç, Ömer Zühtü Yöndem, B. Yüksel, T. Akbaş, O. Balbay, E. Aydın, F. Aydın, Nilgün Mendil, S. Turan, H. Dal, Y. Dikmen, E. Erdoğan, Serdar Akpınar, G. Aygencel, M. Turkoglu, Nur Karaaslan, S. Izdes, H. Demir, N. Şenoğlu, Burcu Sayan, C. Kıraklı, R. Kayali, Pervin Korkmaz, F. Bacakoğlu, F. Koşar
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引用次数: 2

摘要

目的:高流量鼻吸氧作为一种氧支持疗法在国内外得到了广泛的应用。在我们的研究中,我们旨在评估土耳其成人icu中接受HFNO治疗的患者的临床特点、适应症和结果。方法:该多中心前瞻性观察研究于2018年1月15日至2019年1月15日进行,包括14个中心。结果:298例患者入组,平均年龄65.8±17.1岁,其中男性172例(57.7%)。APACHE II和SOFA评分分别为22.5±7.8分和5.8±3.4分。患者发病时平均呼吸频率26.2±7.6次/min, SpO2 89.3±8.2%,中位呼吸困难评分为7分。220例(73.8%)患者使用HFNO的最常见适应症是呼吸衰竭。其他适应症为57例(29.8%)患者存在术后呼吸衰竭风险,17例(5.7%)患者存在缓解目的。1型低氧血症性呼吸衰竭是呼吸衰竭最常见的原因(70.8%)。HFNO中位给药时间4[1-21]天,中位初始流量54 L/min,中位起始FiO2为60%。初始呼吸速率(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
High Flow Nasal Oxygen Therapy Usage in the Adult Intensive Care Units in Turkey: Multi-center, Prospective Study
Aim: High flow nasal oxygen (HFNO) is widely used all over the world as oxygen support therapy. In our study, we aimed to evaluate the clinical characteristics of the patients treated with HFNO therapy, indications and results of HFNO therapy in adult ICUs of Turkey. Method: This multicenter, prospective, observational was conducted between 15 January 2018 and 15 January 2019 and included 14 centers. Results: The study included 298 patients with a mean age of 65.8±17.1 years, 172 (57.7%) of the patients were male. APACHE II and SOFA scores were 22.5±7.8 and 5.8±3.4 respectively. The mean respiratory rate of the patients at the onset of HFNO was 26.2±7.6 breaths/min, SpO2 89.3±8.2% and median Dyspnea score was 7. Most common indication for the use of HFNO was respiratory failure in 220 (73.8%) patients. Other indications were the risk of post-operative respiratory failure in 57 (29.8%) patients, palliative purposes in 17 (5.7%) patients. Type 1 hypoxemic respiratory failure was most common reason for respiratory failure (70.8%). Median HFNO administration time 4 [1-21] days, median initial flow rate was 54 L/min, and median initiation FiO2 was 60%. Initial respiratory rate (p
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