Granulomatous amoebic encephalitis presenting as a solitary mass lesion

Granulomatous amoebic encephalitis is a rare progressive infectious disease of the central nervous system with a high mortality rate. It usually presents as multiple ring-enhancing lesions in the brain with surrounding edema evident, while the granulomatous amoeba encephalitis reported in this case is manifested as a solitary mass in the right frontal lobe mimicking intracranial tumors. For the same disease with different imaging manifestations, clinical diagnosis of granulomatous amoeba encephalitis is difficult and may delay the diagnosis and treatment, resulting in increased mortality. The purpose of this article is to raise awareness of this disease and avoid misdiagnosis, given that early diagnosis is crucial for the correct treatment of patients.