妊娠期炎症性肠病

D. Cudalbă, A. Ciobanu, C. Gică, Mihaela Demetrian, B. Cimpoca-Raptis, G. Peltecu, R. Botezatu, N. Gică, A. Panaitescu
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摘要

炎症性肠病(IBD)有两种主要形式,克罗恩病和溃疡性结肠炎,其特征是胃肠道的慢性炎症。它经常在育龄期被诊断出来,它与妊娠期的重叠增加了疾病管理的复杂性。这篇综述文章旨在总结迄今为止公认的妊娠期IBD,提供最新的信息。对有关妊娠期IBD的期刊文章和指南进行了系统的文献电子检索。对于患有IBD的孕妇来说,最有利的妊娠结局发生在疾病在受孕和妊娠期间都得到缓解的时候。大多数IBD药物在怀孕期间被认为是安全的,在怀孕期间继续治疗是获得最佳结果的基础。妊娠期活动性IBD的适当管理需要多学科护理以降低不良后果。患者对如何优化妊娠结局的认识不足。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inflammatory bowel disease in pregnancy
Inflammatory bowel disease (IBD), with its two main forms, Crohn’s disease, and ulcerative colitis, are characterized by chronic inflammation of the gastrointestinal tract. It is frequently diagnosed during childbearing years and its overlapping with pregnancy adds more complexity to the management of the disease. This review article aims to summarize what is acknowledged so far regarding IBD in pregnancy, providing up-to-date information. A systematic literature electronic search for journal articles and guidelines regarding IBD during pregnancy was undertaken. The most favorable pregnancy outcomes for pregnant women with IBD occur when the disease is in remission both at the time of conception and during the pregnancy. Most of IBD medication is considered safe during pregnancy and continuing therapy in pregnancy is fundamental for achieving optimal outcomes. Proper management of active IBD in pregnancy requires multidisciplinary care to lower adverse outcomes. There is insufficient knowledge among patients regarding how their pregnancy outcomes could be optimized.
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