正调控域16 rs2651899多态性与常见偏头痛亚型的关联:一项Meta分析

Headache: The Journal of Head and Face Pain Pub Date : 2020-01-01 DOI:10.1111/head.13670

Hsun-Hua Lee, Chih-Chung Chen, J. Ong, Yuan-Feng Lin, F. Lee, Chaur-Jong Hu, Yuan-Hung Wang

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引用次数: 4

摘要

偏头痛是一种复发性头痛的神经血管疾病。PRDM16基因的多态性(rs2651899)与偏头痛有关，在最近的全基因组关联研究中被发现。PRDM16 rs2651899多态性在偏头痛中的潜在作用尚不清楚。因此，我们进行了系统回顾和荟萃分析来研究这个问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Association of rs2651899 Polymorphism in the Positive Regulatory Domain 16 and Common Migraine Subtypes: A Meta‐Analysis

Migraine is a neurovascular disease with recurrent headache attacks. A polymorphism (rs2651899) of the PRDM16 gene, which is associated with migraine, was identified in recent genome‐wide association studies. The potential role of the PRDM16 rs2651899 polymorphism in migraine is still unknown. Therefore, we conducted this systematic review and meta‐analysis to examine this issue.

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Headache: The Journal of Head and Face Pain

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