胰腺癌的光谱筛查

Krzysztof Szymoński , Ewelina Lipiec , Kamila Sofińska , Katarzyna Skirlińska-Nosek , Katarzyna Milian-Ciesielska , Joanna Szpor , Michał Czaja , Sara Seweryn , Natalia Wilkosz , Giovanni Birarda , Federica Piccirilli , Lisa Vaccari , Marek Szymoński
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引用次数: 10

摘要

胰腺癌是世界上最具侵袭性和致死率的恶性肿瘤之一,其5年生存率仍低于10%。虽然有很多原因,但其中一个肯定是缺乏早期和独特的胰腺癌筛查诊断工具,这在某种程度上与对癌症分子性质缺乏足够的了解有关。本文旨在证明应用分子光谱方法,包括FTIR高光谱成像和拉曼高光谱制图,结合适当的组织预处理和分析算法,可以很好地区分良性和恶性胰腺。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spectroscopic screening of pancreatic cancer

Pancreatic cancer is one of the most aggressive and lethal malignant neoplasms in the world and 5-year survival rate still remains below 10%. Although, there are many reasons for that, one definitely is the lack of early and unique diagnostic tools for pancreatic cancer screening, which somehow correlates with no sufficient knowledge about cancer’s molecular nature. This article aims to prove the concept that an application of molecular spectroscopic methods including FTIR hyperspectral imaging and Raman hyperspectral mapping, combined with proper tissue pre-processing and analytical algorithms, allows differentiating benign and malignant pancreatic glands with good precision.

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