5-氟尿嘧啶诱发的白质脑病。

IF 1.4 4区医学 Q4 ONCOLOGY

Journal of cancer research and therapeutics Pub Date : 2023-10-01 Epub Date: 2023-01-12 DOI:10.4103/jcrt.jcrt_2165_21

Muthu Manikandan, Biju Azariah, Rajiv Sharma

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摘要

摘要：5-氟尿嘧啶（5FU）诱发的白质脑病的发病率是

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5-Fluorouracil-induced leukoencephalopathy.

Abstract: The incidence of 5-Fluorouracil (5FU)- induced leukoencephalopathy is <5% among the patients treated with this agent. It may present with disorientation, confusion, agitation, seizure, and coma. It should be suspected when patients present with any of these symptoms during or immediately after 5FU chemotherapy. Early detection of drug-induced leukoencephalopathy is important as the clinical symptoms can be reversed by early discontinuation of the drug. Therefore, clinicians should be aware of the possibility of this adverse neurologic effect of 5FU. We describe the case of a 35-year-old female with carcinoma esophagus with 5FU-induced leukoencephalopathy.

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来源期刊

Journal of cancer research and therapeutics ONCOLOGY-

CiteScore

1.80

自引率

15.40%

发文量

299

审稿时长

6 months

期刊介绍： The journal will cover technical and clinical studies related to health, ethical and social issues in field of Medical oncology, radiation oncology, medical imaging, radiation protection, non-ionising radiation, radiobiology. Articles with clinical interest and implications will be given preference.