一例罕见的成人皮下环状肉芽肿病例;病例报告

IF 0.2 Q4 DERMATOLOGY
Waleed Alajroush , Mohammad Abuabat
{"title":"一例罕见的成人皮下环状肉芽肿病例;病例报告","authors":"Waleed Alajroush ,&nbsp;Mohammad Abuabat","doi":"10.1016/j.jdds.2016.02.003","DOIUrl":null,"url":null,"abstract":"<div><p>We are reporting a 33-year old woman with multiple skin-colored, firm, non-tender nodules of varying sizes (ranging between 1 and 1.5<!--> <!-->cm), with limited mobility and normal overlying skin. They were distributed mainly on the palmer side of the fingers. History and laboratory examination indicated lack of systemic diseases such as diabetes, rheumatoid arthritis, and tuberculosis. Histopathologic examination confirmed the subcutaneous granuloma annulare (SGA) diagnosis by showing a normal epidermis with palisading granulomas (histocytes and giant cells) surrounding small areas of connective tissue degeneration (central necrobiosis) and mucin accumulation in the reticular dermis and subcutaneous tissues. The patient responded well to two-session course of intra-lesional steroid injections. SGA should be considered by dermatologists in the differential diagnosis of subcutaneous nodules even without concomitant systemic disease and with rare presentation.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"20 2","pages":"Pages 142-145"},"PeriodicalIF":0.2000,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2016.02.003","citationCount":"0","resultStr":"{\"title\":\"A rare presentation of subcutaneous granuloma annulare in an adult patient; A case report\",\"authors\":\"Waleed Alajroush ,&nbsp;Mohammad Abuabat\",\"doi\":\"10.1016/j.jdds.2016.02.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>We are reporting a 33-year old woman with multiple skin-colored, firm, non-tender nodules of varying sizes (ranging between 1 and 1.5<!--> <!-->cm), with limited mobility and normal overlying skin. They were distributed mainly on the palmer side of the fingers. History and laboratory examination indicated lack of systemic diseases such as diabetes, rheumatoid arthritis, and tuberculosis. Histopathologic examination confirmed the subcutaneous granuloma annulare (SGA) diagnosis by showing a normal epidermis with palisading granulomas (histocytes and giant cells) surrounding small areas of connective tissue degeneration (central necrobiosis) and mucin accumulation in the reticular dermis and subcutaneous tissues. The patient responded well to two-session course of intra-lesional steroid injections. SGA should be considered by dermatologists in the differential diagnosis of subcutaneous nodules even without concomitant systemic disease and with rare presentation.</p></div>\",\"PeriodicalId\":43409,\"journal\":{\"name\":\"Journal of Dermatology & Dermatologic Surgery-JDDS\",\"volume\":\"20 2\",\"pages\":\"Pages 142-145\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2016-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.jdds.2016.02.003\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Dermatology & Dermatologic Surgery-JDDS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352241016000062\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Dermatology & Dermatologic Surgery-JDDS","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352241016000062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

我们报告一位33岁的女性,她有多个不同大小的皮肤颜色,坚硬,不柔软的结节(范围在1到1.5厘米之间),活动能力有限,覆盖皮肤正常。它们主要分布在手指的内侧。病史及实验室检查显示无糖尿病、类风湿关节炎及肺结核等全身性疾病。组织病理学检查证实了皮下环状肉芽肿(SGA)的诊断,显示正常表皮伴栅栏状肉芽肿(组织细胞和巨细胞),周围有小范围的结缔组织变性(中央坏死性坏死)和网状真皮和皮下组织的粘蛋白积聚。患者对两疗程的病灶内类固醇注射反应良好。皮肤科医生在鉴别诊断皮下结节时应考虑SGA,即使没有伴随全身性疾病和罕见的表现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A rare presentation of subcutaneous granuloma annulare in an adult patient; A case report

We are reporting a 33-year old woman with multiple skin-colored, firm, non-tender nodules of varying sizes (ranging between 1 and 1.5 cm), with limited mobility and normal overlying skin. They were distributed mainly on the palmer side of the fingers. History and laboratory examination indicated lack of systemic diseases such as diabetes, rheumatoid arthritis, and tuberculosis. Histopathologic examination confirmed the subcutaneous granuloma annulare (SGA) diagnosis by showing a normal epidermis with palisading granulomas (histocytes and giant cells) surrounding small areas of connective tissue degeneration (central necrobiosis) and mucin accumulation in the reticular dermis and subcutaneous tissues. The patient responded well to two-session course of intra-lesional steroid injections. SGA should be considered by dermatologists in the differential diagnosis of subcutaneous nodules even without concomitant systemic disease and with rare presentation.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
17
审稿时长
16 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信