脑类器官的最新进展

Q4 Medicine

中华神经医学杂志 Pub Date : 2019-10-15 DOI:10.3760/CMA.J.ISSN.1671-8925.2019.10.022

Jing Lu, Dongmei Zhang, Qingxia Huang, Tianye Lan, Peng Xu, Jian Wang

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引用次数: 0

摘要

三维人脑器官是近年来研究人员在标准组织培养室中实现的体外培养器官。它的生长和发育与人类大脑的内源性发育程序非常相似。三维人脑器官可以促进人们对人脑特征的认识，从而对人脑神经精神疾病进行更深入的研究。本文综述了三维人脑器官的发展、应用、障碍和前景。关键词:三维体外培养;脑瀑样;阿尔茨海默病

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Recent advance in cerebral organoids

The 3D human brain organ is an in vitro cultured organ that can be implemented by a researcher in recent years in a standard tissue culture chamber. Its growth and development is very similar to the endogenous developmental program of the human brain. The 3D human brain organs can promote people's understanding of human brain characteristics, and thus, conduct more in-depth research on human brain neuropsychiatric diseases. This is a review of the development, application, obstacles and prospects of 3D human brain organs. Key words: 3D in vitro culture; Cerebral organoid; Alzheimer's disease

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来源期刊

中华神经医学杂志 Psychology-Neuropsychology and Physiological Psychology

CiteScore

0.30

自引率

0.00%

发文量

6272

期刊介绍：