Shawn Wen, Katherine N. Tom, Y. Etoom, Jonathan P. Wong, R. Moodie, I. Al-Hashmi, L. Brandão, Peter D Wong
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Arm Swelling From Subclavian Vein Thrombosis: Factor V Leiden Mutation
Factor V Leiden is a genetic condition that can decrease natural anticoagulant effect in response to activated protein C, increasing thromboembolic risk. We report a 17-year-old man, homozygous for the Factor V Leiden mutation, with sudden onset arm stiffness, pain and swelling caused by a deep vein thrombosis in the subclavian vein. Pediatricians should consider thromboembolic diseases in cases of spontaneous acute limb discomfort and discoloration with no obvious cause. Int J Clin Pediatr. 2020;9(1):1-3 doi: https://doi.org/10.14740/ijcp343