黄嘌呤代替。2. 一些(2-羟基烷基)茶碱三甲基铵的制备及其性质。

Journal of the American Pharmaceutical Association. American Pharmaceutical Association Pub Date : 1960-08-01 DOI:10.1002/JPS.3030490813

F. Vidal, T. Fand

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引用次数: 0

摘要

为大规模制备(2-羟乙基)三甲基茶碱铵提供了一种简便的新方法。几种(2-羟基烷基)三甲基茶碱铵的合成是通过将三甲胺加到各种环氧烷烃上，然后与茶碱或8-取代茶碱衍生物反应得到的中间体。描述了这些化合物的各种性质。

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Substituted xanthines. 2. Preparation and properties of some (2-hydroxyalkyl)trimethylammonium theophyllinates.

A new and convenient method has been developed for the large scale preparation of (2-hydroxyethyl)trimethylammonium theophyllinate. 1 The synthesis of several (2-hydroxyalkyl)trimethylammonium theophyllinates was accomplished by the addition of trimethylamine to various epoxyalkanes and then reacting the resulting intermediate with theophylline or 8-substituted theophylline derivatives. Various properties of these compounds are described.

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Journal of the American Pharmaceutical Association. American Pharmaceutical Association

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