Engerix-B疫苗致短暂性乙型肝炎表面抗原血症1例报告及文献复习

Sam, ika Saparamadu Aadn, Joanne Lee, Lui Tt, Choong-Weng Lam
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引用次数: 2

摘要

本报告描述了一例乙型肝炎表面抗原(HBsAg)阳性的病例,接种乙型肝炎(HepB)疫苗后,在开始血液透析(HD)之前进行了阴性的抗乙型肝炎筛查。文献中报道的HepB疫苗接种后HBsAg血清阳性的变化归因于所接种的HepB疫苗类型、疫苗剂量、用于检测的免疫测定方法和药代动力学。该病例的临床意义、并发症和HBsAg血清阳性持续时间进一步证实了疫苗接种后乙型肝炎表面(HBs)抗原血症的现有证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Engerix-B Vaccine Induced Transient Hepatitis B Surface Antigenemia: A Case Report and Review of the Literature
This report describes a case of positive hepatitis B Surface Antigen (HBsAg) following immunization with hepatitis B (HepB) vaccine, which was administered as indicated by negative anti-HBs screen performed prior to initiation of hemodialysis (HD). Variations in HBsAg seropositivity following HepB vaccination reported in the literature has been attributed to the type of HepB vaccine administered, vaccine dose, method of immunoassay used for testing and pharmacokinetics. Clinical implications, complications and the duration of HBsAg seropositivity of this case further affirms current evidence on hepatitis B Surface (HBs) antigenemia following vaccination.
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