{"title":"lncRNA MEG3作为miR-21的ceRNA在癌症中的作用","authors":"Xing Li, Junxing Huang","doi":"10.3760/CMA.J.ISSN.1673-422X.2020.01.006","DOIUrl":null,"url":null,"abstract":"Long non-coding RNA (lncRNA)-maternally expressed gene 3 (MEG3) and microRNA-21 (miR-21) have been widely recognized as tumor suppressor and promoter. The competing endogenous RNA (ceRNA) hypothesis provides a new strategy for studying the interaction of RNAs. In recent years, studies have shown that MEG3 can play an important role in the occurrence, development, proliferation, metastasis, drug resistance and prognosis of breast cancer, cervical cancer, gastric cancer, lung cancer, leukemia and other malignant tumors as the ceRNA of miR-21. \n \nKey words: \nNeoplasms; RNA, long noncoding; Competing endogenous RNA; Maternally expressed gene 3","PeriodicalId":16120,"journal":{"name":"国际肿瘤学杂志","volume":"199 1","pages":"35-38"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Role of lncRNA MEG3 as ceRNA of miR-21 in cancer\",\"authors\":\"Xing Li, Junxing Huang\",\"doi\":\"10.3760/CMA.J.ISSN.1673-422X.2020.01.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Long non-coding RNA (lncRNA)-maternally expressed gene 3 (MEG3) and microRNA-21 (miR-21) have been widely recognized as tumor suppressor and promoter. The competing endogenous RNA (ceRNA) hypothesis provides a new strategy for studying the interaction of RNAs. In recent years, studies have shown that MEG3 can play an important role in the occurrence, development, proliferation, metastasis, drug resistance and prognosis of breast cancer, cervical cancer, gastric cancer, lung cancer, leukemia and other malignant tumors as the ceRNA of miR-21. \\n \\nKey words: \\nNeoplasms; RNA, long noncoding; Competing endogenous RNA; Maternally expressed gene 3\",\"PeriodicalId\":16120,\"journal\":{\"name\":\"国际肿瘤学杂志\",\"volume\":\"199 1\",\"pages\":\"35-38\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"国际肿瘤学杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1673-422X.2020.01.006\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"国际肿瘤学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-422X.2020.01.006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Long non-coding RNA (lncRNA)-maternally expressed gene 3 (MEG3) and microRNA-21 (miR-21) have been widely recognized as tumor suppressor and promoter. The competing endogenous RNA (ceRNA) hypothesis provides a new strategy for studying the interaction of RNAs. In recent years, studies have shown that MEG3 can play an important role in the occurrence, development, proliferation, metastasis, drug resistance and prognosis of breast cancer, cervical cancer, gastric cancer, lung cancer, leukemia and other malignant tumors as the ceRNA of miR-21.
Key words:
Neoplasms; RNA, long noncoding; Competing endogenous RNA; Maternally expressed gene 3
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
