四肢肌肉骨骼肿瘤:尼日利亚三级医院管理的挑战和结果

O. Salawu, O. Babalola, G. Ibraheem, C. Nwosu, A. Suleiman, D. Kadir, B. Ahmed, J. Mejabi, A. Fadimu, T. Adeyemi, W. Olawole
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引用次数: 1

摘要

背景:发展中国家的肌肉骨骼肿瘤患者往往到医院较晚,这给治疗带来了严重的挑战,尤其是恶性肿瘤。本研究的目的是强调在研究期间在尼日利亚三级卫生中心看到的各种类型的肌肉骨骼四肢肿瘤,在管理它们时遇到的挑战,以及管理的结果。材料和方法:一项前瞻性研究,招募了2015年4月至2017年3月期间到中心就诊的所有同意的四肢肌肉骨骼肿瘤患者。结果:72例患者在研究期间得到管理。平均年龄22.1±4.5岁,11 ~ 20岁年龄组发病最多,共22例(30.6%)。男女比例为1.6:1。股骨是最常见的受累骨。良性肿瘤40例,恶性肿瘤32例。骨软骨瘤是最常见的良性肿瘤,骨肉瘤是最常见的恶性肿瘤。在管理过程中遇到的挑战是演讲晚了,贫穷,和传统的接骨师在演讲前的干预。所有良性肿瘤患者均行手术切除,预后良好。20例(62.5%)恶性肿瘤患者行了消融手术,其中2例在治疗后6个月内死亡,12例(37.5%)恶性肿瘤患者拒绝治疗。结论:由于上述挑战,在我国这一地区,四肢肌肉骨骼肿瘤的治疗非常具有挑战性,特别是恶性类型。有必要提高对这种疾病的认识,政府应该补贴这种疾病的管理费用,并且有必要对人员进行更多的专业培训,以便适当地管理这种疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Musculoskeletal tumors of the extremities: Challenges and outcome of management in a Nigeria Tertiary Hospital
Background: Patients with musculoskeletal tumors in developing countries often present late to the hospital and this poses serious challenges to the management, especially for malignant tumors. This study aims to highlight the various types of musculoskeletal extremity tumors seen in a Nigerian tertiary health center during the study period, the challenges encountered in managing them, and the outcome of the management. Materials and Methods: A prospective study in which all consenting patients with musculoskeletal extremity tumors who presented to the center from April 2015 to March 2017 were recruited. Results: Seventy-two patients were managed during the study period. The mean age was 22.1 ± 4.5 years and the age group most affected was the 11–20 years group, n = 22 (30.6%). Male-to-female ratio was 1.6:1. The femur was the most commonly involved bone. Forty tumors were benign while 32 were malignant tumors. Osteochondroma was the most common benign tumor while osteosarcoma was the most common malignant tumor. The challenges encountered during the management were a late presentation, poverty, and traditional bonesetter intervention before the presentation. Patients with benign tumor had excision with good outcome in all. Twenty (62.5%) of the patients with a malignant tumor had the ablative procedure, two of these 20 patients died within 6 months of treatment, while 12 (37.5%) of the patients with malignant tumor refused the treatment. Conclusion: Management of musculoskeletal extremity tumors is highly challenging in this part of the country, especially the malignant types, due to the challenges mentioned. There is a need for more awareness about the disease, the Government should subsidize the cost of management of this disease, and more specialty training of personnel is necessary for appropriate management of the diseases.
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